TEI 5624

specific inhibitor of human leukocyte elastase; structure given in first source

Also Known As:

7-(4-chlorophenylsulfonyl-L-glutamyl)amino-5-methyl-2-isopropylamino-4H-3,1-benzoxazin-4-one; TEI-5624; Pentanoic acid, 4-(((4-chlorophenyl)sulfonyl)amino)-5-((5-methyl-2-((1-methylethyl)amino)-4-oxo-4H-3,1-benzoxazin-7-yl)amino)-5-oxo-, (S)-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - TEI 5624: 1
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - TEI 5624: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxazines: 9
    - Benzoxazines: 58
      - TEI 5624: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzoxazines: 58
      - TEI 5624: 1

Related Diseases

1.	Emphysema 05/01/1993 - "HSE-induced emphysema in hamsters was also prevented by TEI-5624 (1 mg/kg) administered intratracheally 7 hr after HSE administration (1 mg/kg). "