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5-ethylamino-9- diethylaminobenzo(a)phenoxazinium

structure in first source; RN refers to the chloride salt

Also Known As:

5-ethylamino-9- diethylaminobenzo(a)phenoxazinium chloride; EtNBA

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxazines: 9
    - 5-ethylamino-9- diethylaminobenzo(a)phenoxazinium: 2

Experts

1.	Black, P M: 1 article (01/2001)
2.	Cincotta, L: 1 article (01/2001)
3.	Foley, J W: 1 article (01/2001)
4.	Nikas, D C: 1 article (01/2001)
5.	Speelman, O C: 1 article (01/2001)
6.	Star, W M: 1 article (01/2001)
7.	Witjes, M J: 1 article (01/2001)
8.	van Staveren, H J: 1 article (01/2001)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2001 - "The present in vivo study demonstrates that EtNBA is a safe and effective photodiagnostic agent, able to demarcate U87-MG solid tumors in mice on a real-time basis at a concentration of 2.5-5.0 mg/kg 1-3 hours after administration." 01/01/2001 - "EtNBA localizes in the transplantable solid tumor, but is not targeted specifically to the dysplastic location in the rat palate and mouse skin. " 01/01/2001 - "The pharmacokinetics and tissue-localizing properties were investigated in a rat palate model with chemically induced premalignant mucosal lesions (0.5 mg/kg EtNBA intravenous [i.v.]), a hairless mouse model with UVB-induced premalignant skin lesions (1 mg/kg EtNBA intraperitoneal) and in a rat skin-fold observation chamber model on the back of a rat with a transplanted solid tumor (2.5 mg/kg EtNBA i.v.). "
2.	Glioma (Gliomas) 01/01/2001 - "We have employed EtNBA, a lipophilic, fluorescent benzophenoxazine dye, in a murine model to image subcutaneous and intracranial U-87 glioma implants. "

Related Drugs and Biologics

1.	Coloring Agents (Dyes)