10/06/1995 - "Our preliminary results indicate that oncopterin could be a most sensitive marker for cancer."
01/01/1993 - "The concentrations of oncopterin, N2-(3-aminopropyl)biopterin, a new pterin compound, were determined in urine from various cancer patients by HPLC on a reverse-phase or ion-exchange column. "
01/01/1993 - "Elevated levels of oncopterin, N2-(3-aminopropyl)biopterin, a new pterin compound, in urine from patients with solid and blood cancers."
03/28/1997 - "The content of urinary oncopterin from cancer patients is supposed to be very low, with less than 1 mumol/mol creatinine. "
01/01/1993 - "Oncopterin may thus be a new biochemical marker of some types of cancer."
|2.||Stomach Neoplasms (Stomach Cancer)
03/28/1997 - "Furthermore, oncopterin was not detectable by this HPLC-fluorimetric method in urine samples from patients with stomach cancer who were not treated with methotrexate. "
03/28/1997 - "We now have observed that an unknown substance, which may be derived from methotrexate, in urine from a patient with stomach cancer interfered with the assay of oncopterin and demonstrated that oncopterin could be completely separated from the unidentified substance by HPLC using a Nucleosil 100-5SA strong cation-exchange column. "
|3.||Biological Markers (Surrogate Marker)