MTT formazan

a blue MEM-insoluble mitochondrial byproduct; used to determine viability of cells with active mitochondrial dehydrogenase enzymes

Also Known As:

3-(4,5-dimethylthiazol 2-yl)-2,5-diphenyltetrazolium formazan

Networked: 14 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Azo Compounds: 333
  - Formazans: 125
    - MTT formazan: 14
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Tetrazoles: 14
      - Tetrazolium Salts: 107
        MTT formazan: 14

Experts

1.	Bouraoui, Abderrahman: 2 articles (01/2014 - 12/2011)
2.	Mhadhebi, Lamia: 2 articles (01/2014 - 12/2011)
3.	Mhadhebi, Amel: 1 article (01/2014)
4.	Robert, Jacques: 1 article (01/2014)
5.	Abdulghani, Mahfoudh: 1 article (02/2013)
6.	Al-Rofaai, A: 1 article (02/2013)
7.	Rahman, W A: 1 article (02/2013)
8.	Laroche-Clary, Audrey: 1 article (12/2011)
9.	Robert, Jacque: 1 article (12/2011)
10.	Liu, Yuanbin: 1 article (10/2006)

Related Diseases

1.	Photosensitivity Disorders (Photodermatitis) 01/11/2023 - "Several key factors were investigated during this study, the optimum parameters were: (i) a blue LED light source (λ em = 455 nm) at 6.69 mW; (ii) a pH of 6 mimicking the tumoral environment; (iii) an air-saturated atmosphere reaction medium, (iv) a tetrazolium dye (MTT) was used to monitor the photosensitization efficacy via the generation of the colored MTT-formazan product. "
2.	Neoplasms (Cancer) 05/15/1991 - "A correlation was established between the D-glucose concentration of the culture medium at the time of assay and the production of MTT formazan for cell lines representing seven tumor histologies. " 06/01/1999 - "After treatment with GP-1 and GP-1-H, the inhibitory effects on the growth of mouse transplantable tumors were determined; MTT formazan formation, [3H]deoxythymidine ([3H]TdR) incorporation, cell cycle progression, and mitotic index of SGC-7901 or L1210 cells were measured; the acute toxicity and immune function of mice were assayed. " 01/01/2014 - "The antiproliferative activity was studied on normal cells (MDCK and rat fibroblast) and cancer (A549, MCF7 and HCT15) cell lines by the ability of the cells to metabolically reduce MTT formazan dyes, in comparison to a reference drug the Cisplatin. " 12/01/2011 - "sedoides fractions was evaluated on normal Madin-Darby canine kiney (MDCK), and fibroblast cells and on cancer cell lines (A549, MCF7, and HCT15), using the ability of the cells to metabolically reduce 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) formazan dyes. "
3.	Ischemia 02/01/1997 - "Ischemia of increasing time periods caused a progressive decrease in cellular and mitochondrial MTT reduction in enterocytes and reperfusion showed further decrease of MTT formazan formation. " 03/01/1994 - "Ischemia reduced PMN superoxide anion, MTT formazan, and H2O2 production unless the PMN were adhered to fibronectin or RGDS. "
4.	Synovial Sarcoma (Synovioma) 01/01/1997 - "In the Bax (human synovial sarcoma) cell line MTT colour production by control cells was very low, thus MTT-->formazan production could not be relied upon as a definitive end point equating with cell number. "
5.	Paralysis (Palsy) 02/01/2013 - "The sensitivity of larval paralysis assay (LPA) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide-formazan (MTT-formazan) assay was compared to evaluate the anthelmintic activity of plant extracts. "

Related Drugs and Biologics

1.	Coloring Agents (Dyes)
2.	Thymidine
3.	Vitamin K 3 (Menadione)
4.	Tetracycline (Achromycin)
5.	Superoxides (Superoxide)
6.	Prions
7.	Plant Extracts
8.	Glucose (Dextrose)
9.	Formazans
10.	Fibronectins (Fibronectin)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)