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7- chloro- 2,3- dihydro- 1- (2- methylbenzoyl)- 4(1H)- quinolinone 4-oxime-O-sulfonic acid

structure given in first source; RN given in first source for potassium salt; RN for parent cpd not available 3/93

Also Known As:

M 17055; M-17055; M17055; alilusem; alilusem potassium

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Hydroxylamines: 16
    - Oximes: 1292
      - 7-chloro-2,3-dihydro-1-(2-methylbenzoyl)-4(1H)-quinolinone 4-oxime-O-sulfonic acid: 2
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        7-chloro-2,3-dihydro-1-(2-methylbenzoyl)-4(1H)-quinolinone 4-oxime-O-sulfonic acid: 2

Related Diseases

1.	Cardiomegaly (Heart Hypertrophy) 10/01/1993 - "The effect of M17055 on cardiac hypertrophy was more potent (P < 0.01) than that of captopril, when the comparison was performed at the doses of M17055 and captopril inducing the same extent of blood-pressure decrement. " 11/01/1996 - "Molecular effects of M17055, furosemide and thiazide on cardiac hypertrophy of spontaneously hypertensive rats."
2.	Hypertrophy 10/01/1993 - "We investigated the effects of a novel diuretic, M17055, on blood pressure and cardiovascular hypertrophy in spontaneously hypertensive rats (SHR). " 10/01/1993 - "Beneficial effect of a novel diuretic, M17055, on blood pressure and cardiovascular hypertrophy in spontaneously hypertensive rats."
3.	Hypertension (High Blood Pressure) 10/01/1993 - "These results suggest that M17055 possesses beneficial properties for the clinical treatment of hypertension."
4.	Body Weight (Weight, Body) 10/01/1993 - "The weight of the left ventricle normalized by body weight on the following day of the last dosage was significantly (P < 0.01) reduced by M17055 at doses of 2.5 and 5 mg/kg/day in a dose-dependent manner. "

Related Drugs and Biologics

1.	Thiazides
2.	Furosemide (Lasix)
3.	Diuretics
4.	Captopril (Capoten)