PTK72

a 72 kDa protein-tyrosine kinase; ligation of the B cell antigen receptor leads to the rapid phosphorylation of the enzyme on tyrosine & to the activation of the tyrosine kinase activity of PTK72 for both substrate phosphorylation & autophosphorylation; also undergoes a second phase of tyrosine phosphorylation & activation as B cells progress through the late G(1) phase of the cell cycle

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein-Tyrosine Kinases: 7697
        PTK72: 1
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7697
      - PTK72: 1

Related Diseases

1.	Neoplasms (Cancer) 10/01/1992 - "Fc epsilon RI-mediated tyrosine phosphorylation and activation of the 72-kDa protein-tyrosine kinase, PTK72, in RBL-2H3 rat tumor mast cells."

Related Drugs and Biologics

1.	IgE Receptors (Fc epsilon RI)
2.	Tyrosine (L-Tyrosine)
3.	Protein-Tyrosine Kinases (Tyrosine Kinase)