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Shankhapushpi

ayurvedic antiepileptic preparation; coadministration with phenytoin causes loss of seizure control & lowering of plasma phenytoin levels

Also Known As:

Shankhapushipi

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Pharmaceutical Preparations
- Materia Medica: 248
  - Shankhapushpi: 4

Experts

1.	Chandrashekhar, V M: 1 article (03/2020)
2.	Muchchandi, I S: 1 article (03/2020)
3.	Shalavadi, Mallappa H: 1 article (03/2020)
4.	Antony, Anet: 1 article (01/2019)
5.	Hunasanahally P, Gurushankara: 1 article (01/2019)
6.	Kizhakke P, Anupama: 1 article (01/2019)
7.	Olakkaran, Shilpa: 1 article (01/2019)
8.	Tilagul K, Siddanna: 1 article (01/2019)
9.	Ali, Arshiya: 1 article (10/2015)
10.	Baroudi, Kusai: 1 article (10/2015)

Related Diseases

1.	Alzheimer Disease (Alzheimer's Disease) 01/01/2019 - "Convolvulus pluricaulis (Shankhapushpi) ameliorates human microtubule-associated protein tau (hMAPτ) induced neurotoxicity in Alzheimer's disease Drosophila model."
2.	Serotonin Syndrome (Syndrome, Serotonin) 01/08/2000 - "Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin syndrome in patients who mix St John's wort (Hypericum perforatum) with serotonin-reuptake inhibitors; decreased bioavailability of digoxin, theophylline, cyclosporin, and phenprocoumon when these drugs are combined with St John's wort; induction of mania in depressed patients who mix antidepressants and Panax ginseng; exacerbation of extrapyramidal effects with neuroleptic drugs and betel nut (Areca catechu); increased risk of hypertension when tricyclic antidepressants are combined with yohimbine (Pausinystalia yohimbe); potentiation of oral and topical corticosteroids by liquorice (Glycyrrhiza glabra); decreased blood concentrations of prednisolone when taken with the Chinese herbal product xaio chai hu tang (sho-salko-to); and decreased concentrations of phenytoin when combined with the Ayurvedic syrup shankhapushpi. "
3.	Hypertension (High Blood Pressure) 01/08/2000 - "Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin syndrome in patients who mix St John's wort (Hypericum perforatum) with serotonin-reuptake inhibitors; decreased bioavailability of digoxin, theophylline, cyclosporin, and phenprocoumon when these drugs are combined with St John's wort; induction of mania in depressed patients who mix antidepressants and Panax ginseng; exacerbation of extrapyramidal effects with neuroleptic drugs and betel nut (Areca catechu); increased risk of hypertension when tricyclic antidepressants are combined with yohimbine (Pausinystalia yohimbe); potentiation of oral and topical corticosteroids by liquorice (Glycyrrhiza glabra); decreased blood concentrations of prednisolone when taken with the Chinese herbal product xaio chai hu tang (sho-salko-to); and decreased concentrations of phenytoin when combined with the Ayurvedic syrup shankhapushpi. "
4.	Hemorrhage 01/08/2000 - "Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin syndrome in patients who mix St John's wort (Hypericum perforatum) with serotonin-reuptake inhibitors; decreased bioavailability of digoxin, theophylline, cyclosporin, and phenprocoumon when these drugs are combined with St John's wort; induction of mania in depressed patients who mix antidepressants and Panax ginseng; exacerbation of extrapyramidal effects with neuroleptic drugs and betel nut (Areca catechu); increased risk of hypertension when tricyclic antidepressants are combined with yohimbine (Pausinystalia yohimbe); potentiation of oral and topical corticosteroids by liquorice (Glycyrrhiza glabra); decreased blood concentrations of prednisolone when taken with the Chinese herbal product xaio chai hu tang (sho-salko-to); and decreased concentrations of phenytoin when combined with the Ayurvedic syrup shankhapushpi. "
5.	Epilepsy (Aura) 03/01/2020 - "Convolvulus pluricaulis Choisy commonly known as Shankhapushpi, is traditionally prescribed for nerve debility, loss of memory, epilepsy and as nervine tonic. "

Related Drugs and Biologics

1.	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)
2.	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)
3.	Cyclosporine (Ciclosporin)
4.	Yohimbine (Yocon)
5.	Warfarin (Coumadin)
6.	Antipsychotic Agents (Antipsychotics)
7.	Theophylline (Theon)
8.	Tablets
9.	Prednisolone (Predate)
10.	Phenytoin (Dilantin)