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S 1 (combination)

20  relevant articles (5 outcomes, 10 trials/studies) found for this Bio-Agent

Description: consists of tegafur, 5-chloro-2,4-dihydroxyuridine & potassium oxonate; an inhibitor of fluorouracil(5-FU) degradation; prolongs the blood 5-FU level as well as increases selective toxicity to tumor; used for the treatment of colon cancer

Also Known As:
BMS 247616; BMS247616; S-1 (combination); S-1 cpd; S1-fluoropyrimidine oxoonate combination; S1-tegafur-oxonate combination; TS-1 cpd

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Bio-Agent Context: Research Results

Experts

1. Aridome, Kuniaki: 2 articles (11/2008 - 12/2007)
2. Aikou, Takashi: 2 articles (11/2008 - 12/2007)
3. Ishigami, Sumiya: 2 articles (11/2008 - 12/2007)
4. Hokita, Shuichi: 2 articles (11/2008 - 12/2007)
5. Natsugoe, Shoji: 2 articles (11/2008 - 12/2007)
6. Hamanoue, Masahiro: 1 article (11/2008)
7. Maenohara, Shigeho: 1 article (11/2008)
8. Morita, Satoshi: 1 article (11/2008)
9. Satoh, Kiyoharu: 1 article (11/2008)
10. Takiuchi, Hiroya: 1 article (11/2008)

Related Diseases

1. Stomach Neoplasms (Stomach Cancer)
2. Neoplasm Metastasis (Metastasis)
3. Pancreatic Neoplasms (Pancreatic Cancer)
01/01/2008 - "The GEM/S-1 combination therapy in patients with pancreatic cancer may be promising and should be tested in clinical trials."
01/01/2008 - "The purpose of this study was to evaluate the relationship between different schedules and the effects of GEM/S-1 combination therapy on pancreatic cancer xenograft models. "
04/01/2008 - "Clinical outcome of gemcitabine/S-1 combination therapy for advanced pancreatic cancer."
01/01/2008 - "The studies discussed here include the following: i) a phase I study of a chemotherapy doublet gemcitabine plus capecitabine, combined with a biologic doublet (bevacizumab plus erlotinib) in patients with advanced pancreatic adenocarcinoma (abstract #141); ii) a phase II study of gemcitabine, bevacizumab, and erlotinib in locally advanced and metastatic adenocarcinoma of the pancreas (abstract #151); iii) final results of the multicenter phase II study on gemcitabine, capecitabine, and bevacizumab in patients with advanced pancreatic cancer (abstract #198); iv) interim results from a phase II study of volociximab in combination with gemcitabine in patients with metastatic pancreatic cancer (abstract #142); v) a pilot study of combination chemotherapy with S-1 and irinotecan for advanced pancreatic cancer (abstract #155); vi) a multicenter phase II study of gemcitabine and S-1 combination chemotherapy in patients with unresectable pancreatic cancer (abstract #212); vii) a phase I/II study of PHY906 plus capecitabine in patients with advanced pancreatic carcinoma (abstract #260); and viii) the final results of a phase II trial of Genexol-PM(R), a novel cremophor-free, polymeric micelle formulation of paclitaxel in patients with advanced pancreatic cancer (abstract #269). "
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4. Adenocarcinoma
12/01/2007 - "The successfully curative treatment of advanced gastric adenocarcinoma with multiple liver metastases and paraaortic lymph node metastases by salvage operation following the biweekly paclitaxel and S-1 combination chemotherapy: a case report."
01/01/2008 - "The studies discussed here include the following: i) a phase I study of a chemotherapy doublet gemcitabine plus capecitabine, combined with a biologic doublet (bevacizumab plus erlotinib) in patients with advanced pancreatic adenocarcinoma (abstract #141); ii) a phase II study of gemcitabine, bevacizumab, and erlotinib in locally advanced and metastatic adenocarcinoma of the pancreas (abstract #151); iii) final results of the multicenter phase II study on gemcitabine, capecitabine, and bevacizumab in patients with advanced pancreatic cancer (abstract #198); iv) interim results from a phase II study of volociximab in combination with gemcitabine in patients with metastatic pancreatic cancer (abstract #142); v) a pilot study of combination chemotherapy with S-1 and irinotecan for advanced pancreatic cancer (abstract #155); vi) a multicenter phase II study of gemcitabine and S-1 combination chemotherapy in patients with unresectable pancreatic cancer (abstract #212); vii) a phase I/II study of PHY906 plus capecitabine in patients with advanced pancreatic carcinoma (abstract #260); and viii) the final results of a phase II trial of Genexol-PM(R), a novel cremophor-free, polymeric micelle formulation of paclitaxel in patients with advanced pancreatic cancer (abstract #269). "
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5. Colorectal Neoplasms (Colorectal Cancer)

Related Drugs and Biologics

1. docetaxel (Taxotere)
2. Cisplatin (Platino)
3. irinotecan (Camptosar)
4. Paclitaxel (Taxol)
5. gemcitabine
6. DNA (Deoxyribonucleic Acid)
7. volociximab
8. PHY 906
9. bevacizumab
10. erlotinib (CP 358,774)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Gastrectomy
3. Heterologous Transplantation (Xenotransplantation)
4. Combination Drug Therapy (Combination Chemotherapy)
5. Adjuvant Chemotherapy

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