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HN 11501

thromboxane A2 receptor antagonist

Also Known As:

((5-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)-2-thienyl)oxy)acetic acid; HN-11501; HN11501

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - HN 11501: 1
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - HN 11501: 1
  - Thiophenes: 257
    - HN 11501: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Thiophenes: 257
    - HN 11501: 1

Related Diseases

1.

Thrombosis (Thrombus)

01/01/1992 - "The strongest additive thrombosis-inhibiting effect was observed after oral administration of HN-11501 at a dose of 2.5 mg/kg together with an intravenous infusion of 1 microgram/kg/h of a prostacyclin analogue (cicaprost). "
01/01/1992 - "The antithrombotic effect of a thromboxane A2 receptor antagonist (HN-11501:5-[2-(4-chlorophenylsulfonylamino)-ethyl]-2-thienylox y-acetic acid) alone and in combination with other antithrombotic agents has been studied in an experimental thrombosis model in which laser lesions are used to induce a defined thrombosis in rat mesenteric venules. "

Related Drugs and Biologics

1.	Prostaglandin H2 Thromboxane A2 Receptors
2.	Acetic Acid (Vinegar)
3.	Epoprostenol (Prostacyclin)
4.	Fibrinolytic Agents (Antithrombotic Agents)
5.	cicaprost

Related Therapies and Procedures

1.	Lasers (Laser)
2.	Intravenous Infusions
3.	Oral Administration