tracheloside

a lignan isolated from the seeds of Arctium lappa and Carthamus tinctorius; structure given in first source

Also Known As:

2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)-3-((4-(beta-D-glucopyranosyloxy)-3-methoxyphenyl)methyl)dihydro-3-hydroxy-, (3S-cis)-

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Glucosides: 639
    - tracheloside: 4
Organic Chemicals: 133
- Lactones: 1549
  - 4-Butyrolactone: 81
    - tracheloside: 4
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - 4-Butyrolactone: 81
      - tracheloside: 4

Experts

1.	An, Hailong: 1 article (09/2022)
2.	Bai, Xue: 1 article (09/2022)
3.	Guo, Shuai: 1 article (09/2022)
4.	Kang, Xianjiang: 1 article (09/2022)
5.	Li, Shuting: 1 article (09/2022)
6.	Liu, Xinyi: 1 article (09/2022)
7.	Shi, Sai: 1 article (09/2022)
8.	Hong, Seung-Heon: 1 article (03/2021)
9.	Jeon, Yong-Deok: 1 article (03/2021)
10.	Jin, Jong-Sik: 1 article (03/2021)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 09/01/2022 - "This study found that tracheloside (TCS) was a novel inhibitor of TMEM16A which was specific high expressed in lung cancer tissues. "
2.	Carcinogenesis 10/28/2003 - "These results indicate that tracheloside may not exert significant effects on PhIP-induced mammary carcinogenesis at least under the present experiment condition." 10/28/2003 - "Therefore, chemopreventive effects of tracheloside on the initiation or post-initiation period of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female rats were examined. " 10/28/2003 - "Lack of significant inhibitory effects of a plant lignan tracheloside on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female Sprague-Dawley rats."
3.	Colorectal Neoplasms (Colorectal Cancer) 03/25/2021 - "In Vivo and In Vitro Effects of Tracheloside on Colorectal Cancer Cell Proliferation and Metastasis."
4.	Wounds and Injuries (Trauma) 01/01/2018 - "With western blot results, wound healing with tracheloside occurred through the phosphorylation of ERK1/2. Therefore, tracheloside is a good candidate to promote wound healing and could be developed as a therapeutic agent for wound treatment or used as a leading compound with higher activity."
5.	Neoplasms (Cancer) 03/25/2021 - "Among the phenolic compounds such as tracheloside (TCS) are a major bioactive compound that can combat oxidant stress-related chronic diseases and that also displays anti-tumor activity. "

Related Drugs and Biologics

1.	Lignans
2.	Oxidants (Oxidizing Agents)
3.	Doxorubicin (Adriamycin)
4.	benzocycloheptapyridine
5.	2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridine