|1.||Reed, John C: 7 articles (07/2012 - 12/2003)|
|2.||Chae, Han-Jung: 4 articles (07/2012 - 12/2003)|
|3.||Kim, H-R: 3 articles (01/2014 - 04/2010)|
|4.||Chae, H-J: 3 articles (01/2014 - 04/2010)|
|5.||Kim, Hyung-Ryong: 3 articles (07/2012 - 12/2003)|
|6.||Krajewska, Maryla: 3 articles (05/2012 - 02/2006)|
|7.||Kim, D-S: 2 articles (01/2014 - 04/2010)|
|8.||Lee, Y C: 2 articles (01/2014 - 04/2010)|
|9.||Lee, G-H: 2 articles (01/2014 - 04/2010)|
|10.||Kress, Christina L: 2 articles (01/2011 - 02/2010)|
02/26/2010 - "Because we observed a down-regulation of BI-1 expression in liver and muscle of genetically obese ob/ob and db/db mice as well as in mice with diet-induced obesity in vivo, we investigated the effect of restoring BI-1 expression on metabolic processes in these mice. "
02/26/2010 - "Taken together, these results identify BI-1 as a critical regulator of ER stress responses in the development of obesity-associated insulin resistance and provide proof of concept evidence that gene transfer-mediated elevations in hepatic BI-1 may represent a promising approach for the treatment of type 2 diabetes."
02/26/2010 - "Importantly, BI-1 overexpression by adenoviral gene transfer dramatically improved glucose metabolism in both standard diet-fed mice as well as in mice with diet-induced obesity and, critically, reversed hyperglycemia in db/db mice. "
01/01/2014 - "According to both in vitro and clinical studies, BI-1 promotes the characteristics of cancers. "
02/01/2006 - "Fourteen of 32 tumors (43.8%) were positive for BI-1 gene expression by in situ hybridization. "
05/15/2012 - "Furthermore, BI-1-deficient mice show reduced basal autophagy, and experimentally reducing BI-1 expression impairs tumor xenograft growth in vivo. "
08/01/2003 - "Quantitative real-time reverse transcription-polymerase chain reaction (RT-PCR) on intact RNAs from 17 paired laser-captured microdissected epithelial tissue samples confirmed up-regulated BI-1 expression in 11 of 17 prostate tumors. "
01/01/2015 - "While the effect of BI-1 on apoptosis has been extensively studied, less is known about how BI-1 is related to oncogenesis and the progression, particularly, the invasion and metastasis of cancer. "
05/26/2011 - "This almost universal anti-apoptotic capacity has been shown to be manipulated during infection with enteropathogenic and enterohaemorrhagic Escherichia coli inhibiting host cell death through direct interaction between their effector NleH and BI-1. "
11/01/2006 - "In barley, BI-1 (HvBI-1) expression is induced upon powdery mildew infection and when over-expressed in epidermal cells of barley, HvBI-1 induces susceptibility to the biotrophic fungal pathogen Blumeria graminis. "
01/01/2010 - "The aims of this study were: (1) to clarify the role of intrinsic anti- and pro-apoptotic mediators, evaluating Bax and BI-1 mRNA and protein expressions in liver tissues from patients with different degrees of liver damage; (2) to determine whether HCV and HBV infections modulate said expression. "
01/01/2006 - "Taken together, BI-1 overexpression in the ER is protective in neurons, making BI-1 an interesting target for future studies aiming at the inhibition of neuronal cell death during neurodegenerative diseases and stroke."
01/25/2011 - "In summary, our findings demonstrate that enforced neuronal expression of BI-1 reduces ER stress and provides protection from acute brain injury, suggesting that strategies for enhancing BI-1 expression or activity should be considered for development of new therapies for counteracting the consequences of stroke and acute brain trauma."
01/25/2011 - "Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury."
01/25/2011 - "While brain morphology and vasculature of BI-1 mice appeared to be unchanged from normal non-transgenic mice, BI-1 transgenic mice showed reduced brain lesion volumes and better performance in motoric tests, compared with non-transgenic littermates, in two models of acute brain injury: stroke caused by middle cerebral artery occlusion (MCAO) and traumatic brain injury (TBI) caused by controlled cortical impact. "
|2.||Messenger RNA (mRNA)
|3.||Small Interfering RNA (siRNA)
|6.||Reactive Oxygen Species (Oxygen Radicals)
|8.||RNA (Ribonucleic Acid)
|1.||Heterologous Transplantation (Xenotransplantation)