TIE-2 Receptor

A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).

Also Known As:

Receptor, TIE 2; Receptor, TIE-2; Angiopoietin Receptor Tie-2; TIE-2-RTK; TIE2 Tyrosine Kinase; Tek Receptor; Tie2 Receptor; Angiopoietin Receptor Tie 2; Receptor Tie-2, Angiopoietin; Receptor, Tek; Receptor, Tie2; TIE 2 Receptor Tyrosine Kinase; Tie-2, Angiopoietin Receptor; Tyrosine Kinase, TIE2; TIE-2 Receptor Tyrosine Kinase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein-Tyrosine Kinases: 7697
        Receptor Protein-Tyrosine Kinases: 5999
        TIE Receptors: 42
        TIE-2 Receptor: 232
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Receptor Protein-Tyrosine Kinases: 5999
        TIE Receptors: 42
        TIE-2 Receptor: 232
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7697
      - Receptor Protein-Tyrosine Kinases: 5999
        TIE Receptors: 42
        TIE-2 Receptor: 232

mouse Tek protein

Bio-Agent Context: Research Results