|1.||O'Rourke, Brian: 1 article (08/2008)|
|2.||Liu, Ting: 1 article (08/2008)|
|3.||Pilitsis, Julie G: 1 article (03/2002)|
|4.||O'Regan, Michael H: 1 article (03/2002)|
|5.||Phillis, John W: 1 article (03/2002)|
|6.||Diaz, Fernando G: 1 article (03/2002)|
08/01/2008 - "Treatment with CGP-37157 or lowering [Na+]i prevented the impaired NADH response in heart failure. "
08/01/2008 - "[Ca2+]m accumulation was [Na+]i-dependent; less [Ca2+]m accumulated in cells with 15 Na+ versus 5 mmol/L Na+ and NADH oxidation was evident at 15 mmol/L Na+, but not at 5 mmol/L Na+. Treatment with either the mitochondrial Na+/Ca2+ exchange inhibitor CGP-37157 (1 micromol/L) or raising cytosolic Pi (2 mmol/L) enhanced [Ca2+]m accumulation and prevented the NADH oxidation at 15 mmol/L [Na+]i. In heart failure myocytes, resting [Na+]i increased from 5.2+/-1.4 to 16.8+/-3.1mmol/L and net NADH oxidation was observed during pacing, whereas NADH was well matched in controls. "