1,2,3,4- tetrahydroisoquinoline- 3- carboxylic acid

used as a substitute for amino acids in synthetic peptides

Also Known As:

1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, (+-)-isomer; 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, (S)-isomer; 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, hydrochloride; 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, hydrochloride, (S)-isomer; Tic-AA; tetrahydro-3-isoquinoline carboxylic acid

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoquinolines: 34
      - Tetrahydroisoquinolines: 44
        1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid: 11

Experts

1.	Cativiela, Carlos: 1 article (03/2021)
2.	Matías-Valdez, Lizeth A: 1 article (03/2021)
3.	Ordóñez, Mario: 1 article (03/2021)
4.	Sayago, Francisco J: 1 article (03/2021)
5.	Viveros-Ceballos, José Luis: 1 article (03/2021)
6.	Deodhar, Deepak: 1 article (12/2014)
7.	Khedkar, Priti: 1 article (12/2014)
8.	Kotha, Sambasivarao: 1 article (12/2014)
9.	Fang, Hao: 1 article (12/2010)
10.	Xu, Wenfang: 1 article (12/2010)

Related Diseases

Tics (Tic)

03/01/2021 - "The second strategy involves a radical decarboxylation-phosphorylation reaction on 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic). "
12/07/2014 - "Diversity-oriented synthesis of medicinally important 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) derivatives and higher analogs."
07/03/2000 - "A new synthetic approach to 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) derivatives via a [2 + 2 + 2] cycloaddition reaction."
09/01/1992 - "Preferred conformation of the 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) residue."
12/07/2014 - "1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid (Tic) is a constrained analog of phenylalanine (Phe). "

Related Drugs and Biologics

1.	Phenylalanine (L-Phenylalanine)
2.	Peptides (Polypeptides)
3.	Opioid Peptides (Opioid Peptide)
4.	Opioid Analgesics (Opioids)
5.	2- tyrosyl- 1,2,3,4- tetrahydroisoquinoline- 3- carboxylic acid
6.	Peptidomimetics
7.	delta Opioid Receptors (delta Opioid Receptor)
8.	mu Opioid Receptors (mu Opioid Receptor)
9.	Tyrosine (L-Tyrosine)
10.	Narcotic Antagonists (Opioid Antagonists)