glucan sulfate

RN given refers to (1-3)-beta-D-glucan hydrogen sulfate; empirical formula of the glucan sulfate repeating unit is(C6-H10-O5)8 3SO3NH4(+) 4H2O; see also curdlan sulfate

Also Known As:

(1-3)-beta-D-glucan hydrogen sulfate; glucan sulfate, ammonium salt

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - Biopolymers: 773
    - Glucans: 1624
      - glucan sulfate: 1
Carbohydrates: 22023
- Polysaccharides: 15383
  - Glucans: 1624
    - glucan sulfate: 1

Related Diseases

1.	Sarcoma (Soft Tissue Sarcoma) 11/01/1991 - "Glucan sulfate (250 mg/kg, i.v.) increased (P less than 0.05) median survival time of C57B1/6J mice with syngeneic melanoma B16 or sarcoma M5076. "
2.	Experimental Melanoma 11/01/1991 - "Glucan sulfate (250 mg/kg, i.v.) increased (P less than 0.05) median survival time of C57B1/6J mice with syngeneic melanoma B16 or sarcoma M5076. "
3.	Communicable Diseases (Infectious Diseases) 11/01/1991 - "We concluded that: (1) insoluble beta-1,3-D-glucan can be converted to a water soluble sulfated form; (2) glucan sulfate activates macrophages and stimulates bone marrow; (3) glucan sulfate exerts antitumor therapeutic activity, and (4) glucan sulfate immunoprophylaxis will modify the course of experimental infectious disease."

Related Drugs and Biologics

1.	polysaccharide-K