|1.||Myocardial Ischemia (Ischemic Heart Diseases)
04/01/1995 - "During 30-min ischemia, 1, 3, and 10 mg/L ITF 1300 reduced the incidence of VF concentration dependently, with complete abolition of VF at the highest concentration (p < 0.05). "
04/01/1995 - "Protection by ITF 1300, a heparin ion-pair complex, against arrhythmias induced by regional ischemia and reperfusion in the isolated rat heart: possible mechanism of action."
04/01/1995 - "We examined the effects of the heparin ion-pair complex ITF 1300 on ventricular fibrillation (VF) and other arrhythmias elicited by regional ischemia and by reperfusion in isolated rat hearts (n = 12 per group). "
04/01/1995 - "Left atrial pacing at a rate close to control rate (300 beats/min) abolished the antiarrhythmic effects of ITF 1300 and the QT widening, indicating that bradycardia and QT widening were important in mediating the antiarrhythmic effects. "
04/01/1995 - "ITF 1300 caused concentration-dependent bradycardia, PR interval widening, and QT widening. "