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aspartyltyrosine

Also Known As:

Asp-Tyr

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - aspartyltyrosine: 10

Experts

1.	Liu, Lianliang: 2 articles (06/2013 - 11/2012)
2.	Liu, Lingyi: 2 articles (06/2013 - 11/2012)
3.	Lu, Baiyi: 2 articles (06/2013 - 11/2012)
4.	Zhang, Ying: 2 articles (06/2013 - 11/2012)
5.	Gumienna-Kontecka, Elzbieta: 1 article (03/2016)
6.	Medici, Serenella: 1 article (03/2016)
7.	Ostrowska, Malgorzata: 1 article (03/2016)
8.	Peana, Massimiliano: 1 article (03/2016)
9.	Remelli, Maurizio: 1 article (03/2016)
10.	Zoroddu, Maria Antonietta: 1 article (03/2016)

Related Diseases

1.	Type 2 Diabetes Mellitus (MODY) 07/01/1998 - "However, NIDDM patients with the Tyr allele, which was previously reported to be associated with insulin resistance, tended to have lower BMIs than those without this allele (Asp/Asp: 24.5 +/- 1.1 kg/m2, Asp/Tyr: 22.6 +/- 0.4 kg/m2, Tyr/Tyr: 22.8 + 0.3 kg/m2, P = 0.06 by analysis of variance). " 06/01/2004 - "To study the association of muscle-specific glycogen-targeting regulatory subunit of the glucogen-bound protein phosphatase 1 (PPP1R3) gene codon 905 Asp/Tyr polymorphism with type 2 diabetes in Chinese Han population in Hefei region of Anhui province. " 07/01/1998 - "No significant difference was found in the genotype distribution between NIDDM patients (N = 259; Asp/Asp = 0.10, Asp/Tyr = 0.44, Tyr/Try = 0.46) and healthy control subjects (n = 194; Asp/Asp = 0.13, Asp/Tyr = 0.37, Tyr/Tyr = 0.50) or between patient groups subdivided by the mode of treatment: NIDDM patients with insulin therapy (Asp/Asp = 0.14, Asp/Tyr = 0.46, Tyr/Tyr = 0.40) and those without insulin therapy (Asp/Asp = 0.07, Asp/Tyr = 0.43, Tyr/Tyr = 0.50). "
2.	Breast Neoplasms (Breast Cancer) 08/01/1995 - "We previously identified a codon 351 (Asp-->Tyr) mutant estrogen receptor (ER) in a tamoxifen-stimulated human breast tumor line. " 03/01/1997 - "In this report we describe the regulation of transforming growth factor alpha (TGF alpha) mRNA by estradiol and the antiestrogens keoxifene and ICI 182,780 in our stable transfectants of ER-negative MDA-MB-231 breast cancer cells, which express either the wild-type (S30 cells) or codon 351 asp --> tyr mutant ER (BC-2 cells). "
3.	Body Weight (Weight, Body) 06/12/2013 - "A short-term antihypertensive assay stated that both Asp-Tyr [10 mg day(-1) (kg of body weight)(-1)] and BSP [50 mg day(-1) (kg of body weight)(-1)] could significantly reduce the systolic blood pressure of spontaneously hypertensive rats (3-6 h). " 11/14/2012 - "Asp-Tyr [10 mg/day kg body weight (BW)] and BSP (50 mg/day kg BW) significantly reduced ACE activity in lung at the same level (p < 0.05), while BSP (50 mg/day kg BW) reduced systolic blood pressure (SBP) more effectively for its phenolic compounds, such as ferulic acid and p-coumaric acid, which when combined with ACE inhibitor exert a synergistic effect. "
4.	Sneezing 03/01/1998 - "Intracerebroventricular administration of the peptides kyotorphin (Tyr-Arg), neokyotorphin (Thr-Ser-Lys-Tyr-Arg), and Asp-Tyr at doses of 4 and 8 micrograms altered the behavior of rats in a manner similar to that seen after similar administration of brain fractions from hibernating ground squirrels (Citellus undulatus), which contained these peptides; there were increases in orientational reactions, increases in the frequency of stereotypical scratching movements, grooming, yawning, hiccuping, and sneezing. "
5.	Parkinson Disease (Parkinson's Disease) 03/28/2016 - "A protected 30-amino acid fragment, Acetyl-SPDEKHELMIQLQKLDYTVGFCGDGANDCG-Amide, Acetyl-Ser-Pro-Asp-Glu-Lys-His-Glu-Leu-Met-Ile-Gln-Leu-Gln-Lys-Leu-Asp-Tyr-Thr-Val-Gly-Phe-Cys-Gly-Asp-Gly-Ala-Asn-Asp-Cys-Gly-Amide, encompassing the sequence from residues 1164 to 1193 in the encoded protein from Parkinson's disease gene Park9 (YPk9), was studied for manganese and zinc binding. "

Related Drugs and Biologics

1.	Codon (Codons)
2.	Protein Phosphatase 1
3.	Glycogen
4.	Raloxifene Hydrochloride (Evista)
5.	Estrogen Receptor Modulators (Antiestrogen)
6.	Transforming Growth Factor alpha (TGF-alpha)
7.	Zinc
8.	Tamoxifen
9.	Messenger RNA (mRNA)
10.	Estrogen Receptors

Related Therapies and Procedures

1.	Therapeutics