|1.||Nakabeppu, Yusaku: 2 articles (01/2014 - 06/2007)|
|2.||Carter, Megan: 1 article (01/2015)|
|3.||Desroses, Matthieu: 1 article (01/2015)|
|4.||Page, Brent D G: 1 article (01/2015)|
|5.||Hagenkort, Anna: 1 article (01/2015)|
|6.||Gustafsson, Robert: 1 article (01/2015)|
|7.||Warpman Berglund, Ulrika: 1 article (01/2015)|
|8.||Stenmark, Pål: 1 article (01/2015)|
|9.||Jemth, Ann-Sofie: 1 article (01/2015)|
|10.||Gad, Helge: 1 article (01/2015)|
01/01/2014 - "In cancer cells encountering high oxidative stress levels, a high level of 8-oxo-dGTP accumulates in the nucleotide pool, and cells therefore express increased levels of MTH1 in order to eliminate 8-oxo-dGTP. "
01/01/2015 - "We find that depletion of NUDT15 has no effect on incorporation of 8-oxo-dGTP into DNA and does not impact cancer cell survival in cell lines tested. "
06/01/2007 - "We thus investigated the levels and localization of both 8-oxo-dG accumulation and expression of MTH1, which hydrolyzes 8-oxo-dGTP to prevent its incorporation into DNA, in the thoracic aorta prepared from stroke-prone spontaneously hypertensive rats (SHRSP) and age-matched Wister-Kyoto rats (WKY), aged 5-32 weeks. "
|5.||Chromosome Aberrations (Chromosome Abnormalities)
04/04/2002 - "We also found that the surviving cells displayed an hypermutator phenotype which could be explained by different pathways involving Pol beta, such as (i) an increased capacity to incorporate into DNA the mutagenic dGTP analog, 8-oxo-dGTP, one of the most abundant purine-derived nucleotides exposed to gamma-irradiation, (ii) the induction of IR-induced DNA breaks and (iii) accumulation of chromosome aberrations induced by radiation. "
|2.||DNA (Deoxyribonucleic Acid)
|3.||deoxyguanosine triphosphate (dGTP)