HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
Ro 317467
structure given in first source
Also Known As:
Ro 31-7467; Ro-317467
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Organophosphorus Compounds: 300
Ro 317467: 1
Related Diseases
1.
Bone Resorption
05/15/1995 - "
However, CT1166 (10(-9) M) and Ro 31-7467 (10(-8) M) in combination were required to completely abolish IL-1 alpha-stimulated bone resorption in mouse calvariae throughout a 96 h culture period.
"
05/15/1995 - "
Two low-molecular-mass inhibitors of matrix metalloproteinases (MMPs), CT1166, a concentration-dependent selective inhibitor of gelatinases A and B, and Ro 31-7467, a concentration-dependent selective inhibitor of collagenase, were examined for their effects on bone resorption and type-I collagenolysis.
"
05/15/1995 - "
In 24 h cultures, CT1166 and Ro 31-7467 inhibited both interleukin-1 alpha- (IL-1 alpha; 10(-10) M) and 1,25-dihydroxyvitamin D3 (10(-8) M)-stimulated bone resorption in cultured neonatal mouse calvariae at concentration selective for the inhibition of gelatinase (10(-9) M for CT1166) and collagenase (10(-8) M for Ro 31-7467) respectively.
"
Related Drugs and Biologics
1.
Interleukin-1alpha (Interleukin 1 alpha)
2.
Matrix Metalloproteinases (MMPs)
3.
Gelatinases
4.
Collagenases (Collagenase)
5.
Calcitriol (Calcijex)
6.
CT 1166