|1.||Yagi, Minoru: 2 articles (04/2012 - 11/2003)|
|2.||Fujiwara, Kenji: 2 articles (04/2006 - 10/2004)|
|3.||Inao, Mie: 2 articles (04/2006 - 10/2004)|
|4.||Mochida, Satoshi: 2 articles (04/2006 - 10/2004)|
|5.||Uozaki, Hiroshi: 1 article (10/2014)|
|6.||Takahashi, Yoshihisa: 1 article (10/2014)|
|7.||Watanabe, Masato: 1 article (10/2014)|
|8.||Fukusato, Toshio: 1 article (10/2014)|
|9.||Soejima, Yurie: 1 article (10/2014)|
|10.||Kumagai, Arisa: 1 article (10/2014)|
|1.||Liver Cirrhosis (Hepatic Cirrhosis)
08/01/2004 - "TJ-135 improved liver fibrosis induced in rats by TAA administration. "
06/01/2003 - "The aim of this study was to investigate whether TJ-135 has any influence on the development of preneoplastic lesions as well as liver fibrosis. "
06/01/2003 - "These results indicate that although TJ-135 has anti-apoptotic activity, TJ-135 does not increase preneoplastic lesions but significantly reduces liver fibrosis through the inhibition of stellate cell activation without a reduction of hepatocyte cell death."
08/01/2004 - "TJ-135 and emodin regulate PDGF-dependent events in stellate cells and attenuate the development of liver fibrosis. "
06/01/2003 - "The effects of the TJ-135 were examined using the choline-deficient L-amino acid-defined diet-induced liver fibrosis model. "
11/01/2003 - "The aim of this study is to evaluate the efficacy of the herbal medicine Inchinko-to (TJ-135) on the treatment of liver fibrosis in patients with BA without jaundice, especially from the viewpoint of the long-term effects of TJ-135. "
01/19/2007 - "Chinese herbal medicines, Inchinko-to, Bofu-tsusho-san and Dai-saiko-to, containing 3, 18 and 8 components, respectively, have since long been used as an anti-inflammatory, antipyretic, choleretic and diuretic agent for liver disorders and jaundice, as an anti-obesity agent, a hypocholesterolemic agent for liver disorders and a therapeutic and/or preventive agent for cholesterol gallstone disease with hypertriglycerid-emia in China and Japan, respectively. "
04/01/2012 - "The herbal medicine Inchinko-to reduces hepatic fibrosis in cholestatic rats."
04/04/2006 - "Thus, the induction of HSC apoptosis could be the mechanism how TJ-135 works on the resolution of hepatic fibrosis. "
04/04/2006 - "In the course of clarifying the mechanism, we directed our focus on hepatic stellate cells (HSCs), playing a pivotal role in hepatic fibrosis, and found that rat HSCs cultured with TJ-135 changed their morphology to star-like configuration with thin, slender and dendritic processes with fewer stress fibers, which might be the features in apoptosis. "
06/01/2003 - "TJ-135 prevented fibrosis in a dose-dependent manner up to 1.5% (w/w). "
10/01/2004 - "Oral administration of TJ-135 improved the mortality of rats given CCl4 with reduced extents of liver necrosis and fibrosis. "
|5.||Liver Diseases (Liver Disease)
|3.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|8.||Choline (Choline Chloride)