|1.||Nishikawa, Akiyoshi: 2 articles (03/2008 - 01/2002)|
|2.||Imai, Toshio: 2 articles (01/2007 - 01/2002)|
|3.||Hirose, Masao: 2 articles (01/2007 - 01/2002)|
|4.||Dou, Yannong: 1 article (12/2014)|
|5.||Wei, Zhifeng: 1 article (12/2014)|
|6.||Ye, Jun: 1 article (12/2014)|
|7.||Xia, Yufeng: 1 article (12/2014)|
|8.||Kong, Lingyi: 1 article (12/2014)|
|9.||Song, Ji Hye: 1 article (12/2014)|
|10.||Yang, Yan: 1 article (12/2014)|
12/01/2014 - "For in vivo study, C57BL/6J mice were first fed either a control diet (CON) or high-fat diet (HF) to induce obesity, and then fed CON, HF, or HF with 500 mg/kg BW arctiin (HF + AC) for four weeks. "
12/01/2014 - "These findings suggest that arctiin has a potential benefit in preventing obesity."
11/01/2009 - "Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats."
11/01/2009 - "Arctiin has favorable potency for the development of an inhibitory agent of NF-kappaB and further application to clinical treatment of glomerulonephritis, though clinical studies are required."
11/01/2009 - "In this study, the ameliorative effects of arctiin, a natural compound isolated from the fruits of Arctium lappa, on rat glomerulonephritis induced by cationic bovine serum albumin (cBSA) were determined. "
11/01/2009 - "These findings suggest that the ameliorative effects of arctiin on glomerulonephritis is carried out mainly by suppression of NF-kappaB activation and nuclear translocation and the decreases in the levels of these pro-inflammatory cytokines, while SOD is involved in the inhibitory pathway of NF-kappaB activation. "
|3.||Diabetic Retinopathy (Retinopathy, Diabetic)
08/01/2012 - "Together, these findings demonstrate that arctiin decreases the severity of diabetic complications, demonstrating the importance of this compound as an inhibitor of diabetic retinopathy."
08/01/2012 - "We first extracted arctiin from Fructus Arctii and then investigated its chemopreventive effect on streptozotocin-induced diabetic retinopathy in male Sprague-Dawley rats. "
08/01/2012 - "Effects of arctiin on streptozotocin-induced diabetic retinopathy in Sprague-Dawley rats."
08/01/2012 - "In this study, we investigated the effect of arctiin on the serum glucose and HBA1c levels, the blood viscosity, and VEGF expression in the retinal tissues of rats with diabetic retinopathy. "
03/01/2008 - "Arctiin is a major lignan constituent of Arctium lappa and has anti-cancer properties in animal models. "
01/01/2007 - "Lack of a significant effect of arctiin on development of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats."
03/01/2008 - "Herein we report that arctiin induces growth inhibition and dephosphorylates the tumor-suppressor retinoblastoma protein in human immortalized keratinocyte HaCaT cells. "
01/01/2007 - "In conclusion, weak inhibitory effects of arctiin on DMBA-induced mammary tumor development were suggested in OVX rats, but any further assessment is needed to obtain conclusive results."
01/01/2007 - "To clarify its influence on mammary carcinogenesis, female rats were administrated 7,12-dimethylbenz(a)anthracene (DMBA) once, and when the incidence of palpable mammary tumors reached 50%, subjected to ovariectomy (OVX) and divided into tumor-bearing [DMBA-Tumor (+)] and no-tumor-bearing [DMBA-Tumor (-)] groups, subgroups of each then being fed soybean-free diet containing 0, 40, 200, and 1000 ppm of arctiin for 31 wk. The incidence and multiplicity of palpable tumors in the 200 ppm DMBA-Tumor (+) subgroup from week 12 of arctiin treatment tended to be decreased as compared to the 0 ppm subgroup and at terminal sacrifice, the volume of histopathologically defined mammary tumors was decreased in the 40 ppm DMBA-Tumor (-) subgroup, but again without statistical significance. "
|5.||Body Weight (Weight, Body)
12/01/2014 - "Furthermore, administration of arctiin significantly decreased the body weight in obese mice fed with the high-fat diet. "
12/01/2014 - "Arctiin inhibits adipogenesis in 3T3-L1 cells and decreases adiposity and body weight in mice fed a high-fat diet."
12/01/2014 - "The comparative studies of arctigenin and arctiin (the two main ingredients of ethyl acetate fraction) indicated that arctigenin rather than arctiin could reduce the loss of body weight, disease activity index and histological damage in the colon. "
03/01/1998 - "Male F344 rats were initially injected with diethylnitrosamine (DEN, 200 mg/kg body weight) intraperitoneally and two weeks later were treated with arctiin (1%), EE (1.5 ppm or 5 ppm), 2-AAF (20 ppm), arctiin + EE (1.5 ppm or 5 ppm), or arctiin + 2-AAF (20 ppm) in the diet for 6 weeks and then killed, all rats being subjected to partial hepatectomy at week 3. EE and 2-AAF clearly increased the development of GST-P foci. "
|1.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|2.||NF-kappa B (NF-kB)
|3.||Bovine Serum Albumin
|9.||2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridine