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erythrodiol

Also Known As:

olean-12-ene-3beta,28-diol

Networked: 13 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Pentacyclic Triterpenes: 108
        Oleanolic Acid: 547
        erythrodiol: 13
      - Sapogenins: 26
        Oleanolic Acid: 547
        erythrodiol: 13

Experts

1.	Sánchez-Quesada, Cristina: 2 articles (01/2015 - 01/2011)
2.	Du, Zhichao: 1 article (05/2020)
3.	Shen, Pingping: 1 article (05/2020)
4.	Wang, Wei: 1 article (05/2020)
5.	Wang, Weiwei: 1 article (05/2020)
6.	Xu, Shaohua: 1 article (05/2020)
7.	Yu, Boyang: 1 article (05/2020)
8.	Zhang, Jian: 1 article (05/2020)
9.	Atanasov, Atanas G: 1 article (01/2017)
10.	Dirsch, Verena M: 1 article (01/2017)

Related Diseases

1.	Neoplasms (Cancer) 06/22/2009 - "Overall, we provide a significant insight into the anticarcinogenic action of erythrodiol and uvaol that may have a potential in prevention and treatment of brain tumors and other cancers." 09/15/1988 - "By in vitro experiment monitoring with 12-O-tetradecanoylphorbol-13-acetate-induced stimulation of 32Pi incorporation into phospholipids and an in vivo test on skin tumor formation in mice initiated with 7,12-dimethylbenz[a]anthracene and promoted with 12-O-tetradecanoylphorbol-13-acetate, 18 beta-olean-12-ene-3 beta,28-diol (= erythrodiol), 18 beta-olean-12-ene-3 beta,23,28-triol, 18 alpha-olean-12-ene-3 beta,28-diol, and 18 alpha-olean-12-ene-3 beta,23,28-triol showed remarkable suppressive effects. " 02/12/2023 - "Fractions containing triterpenoid acids plus fernenol, complexes of oleanolic:ursolic acids, and erythrodiol:uvaol were found to be the most potent therapeutic candidates in the management of cancer diseases. " 01/01/2015 - "The present study was designed to elucidate if the four major triterpenes found in virgin olive oil (oleanolic acid, maslinic acid, uvaol, and erythrodiol) are able to enhance M1 macrophage response which represents an important defense mechanism against cancer. "
2.	Atherosclerosis 01/01/2017 - "This bioactivity makes erythrodiol a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis."
3.	Ventricular Remodeling 01/01/2012 - "Erythrodiol and uvaol reduce cardiac hypertrophy and left ventricle remodeling induced by angiotensin II in mice by diminishing fibrosis and myocyte area. "
4.	Rupture 12/01/2015 - "Moreover, erythrodiol-loaded liposomes tended to rupture into single lipid bilayers during scanning. "
5.	Experimental Melanoma 11/01/2016 - "Upon evaluation of the melanogenesis-inhibitory activity in B16 melanoma cells induced with α-melanocyte-stimulating hormone (α-MSH), erythrodiol (7), 4-hydroxy-2-methoxyphenyl β-d-glucopyranoside (13), and butyl quinate (15) exhibited inhibitory effects (65.4 - 86.0% melanin content) with no, or almost no, toxicity to the cells (85.9 - 107.4% cell viability) at 100 μm concentration. "

Related Drugs and Biologics

1.	Triterpenes
2.	uvaol
3.	Oleanolic Acid
4.	Olive Oil
5.	maslinic acid
6.	Reactive Oxygen Species (Oxygen Radicals)
7.	Quinic Acid (Quinate)
8.	Phospholipids (Phosphatides)
9.	Melanocyte-Stimulating Hormones (MSH)
10.	Melanins (Melanin)