BW 10

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9 relevant articles (0 outcomes, 1 trials/studies) found for this Bio-Agent

Description: potently inhibits bombesin evoked release of gastrointestinal hormones in vitro & in vivo

Also Known As:

((des-NH2)Phe(19)-D-Ala(24)-D-Pro(26)psi(CH2NH)Phe(27))-GRP(19-27); (de-NH2)Phe(19)-Ala(24)-Pro(26)psi(CH2NH)-Phe(27)-GRP (19-27); 2258U89; BW 2258U89; BW-10; BW2258U89; GRP (19-27), (de-NH2)Phe(19)-Ala(24)-Pro(26)psi(CH2NH)Phe(27)-; GRP (19-27),(de-NH2)phenylalanyl(19)-alanyl(24)-prolyl(26)psi(CH2NH)-phenylalanine(27)-

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Peptides: 16074

Oligopeptides: 165

BW 10: 9

Related Diseases

1.	Sleep Deprivation 08/01/1990 - "Since during sleep deprivation the animals undergo a reduction in plasma T4 concentration and inability to maintain body temperature heralds death, an identical study was performed in five trios of hyperthyroid rats (hyperD-, hyperC-, and hyper CC-rats) given daily ip injections of 15 micrograms T4/100 g BW, 10 days before and throughout the deprivation period" Get all the results and reference details, order at left...
2.	Small Cell Carcinoma (Small Cell Lung Cancer) 01/01/1995 - "BW2258U89: a GRP receptor antagonist which inhibits small cell lung cancer growth." 04/01/2000 - "BW2258U89 is a gastrin releasing peptide (GRP) receptor antagonist which inhibits the proliferation of the neuroendocrine tumor small cell lung cancer (SCLC)" Get all the results and reference details, order at left...
3.	Neoplasms (Cancer) 01/01/1996 - "A BW1023U90 analogue, BW2258U89 (10 micrograms/day, SC) slowed SCLC xenograft format on in nude mice and [125I] BW 1023U90 localized to SCLC tumors 1 h after injection into nude mice" 07/02/1992 - "Of the 10 different compounds tested, BW-10 or 2258U89 ([de-NH2)Phe19,D-Ala24,D-Pro26 psi(CH2NH)Phe27]-GRP(19-27)) was most potent towards inhibiting bombesin binding to rat pancreatic acinar cancer cells with an ID50 of 0.5 nM. BW-10 (1 and 10 nM) significantly inhibited the gastrin response to 1 nM bombesin, from isolated rat stomach, in vitro, in a dose-dependent fashion" Get all the results and reference details, order at left...
4.	Body Weight (Weight, Body) 03/01/1985 - "Body weight (BW), 10 circumference (C), and 7 skinfold (SF) measurements were obtained preprandial at sea level (SL) and on days 2,4,6,9,12,16, and 18 at HA" 07/01/1997 - "B6C3F1 female mice were treated via oral gavage a total of five times, with 3 weeks between each dosing, with 0, 1, 3, or 10 micrograms 2,3,7,8,-TCDD/kg body weight (bw); 3 or 30 mg 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153)/kg bw; 100, 300, or 1000 micrograms 3,3',4,4',5-pentachlorobiphenyl (PCB 126)/kg bw; 10, 30, or 100 micrograms 2,3,4,7,8-pentachlorodibenzofuran (4-PeCDF)/kg bw; or 2 or 20 mg 1,3,6,8-TCDD/kg at 10 ml/kg bw" Get all the results and reference details, order at left...
5.	Neuroendocrine Tumors (Neuroendocrine Tumor) 04/01/2000 - "BW2258U89 is a gastrin releasing peptide (GRP) receptor antagonist which inhibits the proliferation of the neuroendocrine tumor small cell lung cancer (SCLC)" Get all the results and reference details, order at left...
8 Diseases and 9 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	BW 10
2.	Gastrin-Releasing Peptide
3.	Tetrachlorodibenzodioxin (TCDD)
4.	Pyridinolcarbamate (P23)
5.	Methylcellulose (BFL)
6.	Gastrins
7.	Dihydrotachysterol (AT 10)
8.	Bombesin
9.	BW 1023U90
10.	2,3,4,7,8-pentachlorodibenzofuran
12 Drugs and Important Bio-Agents and 6 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Heterologous Transplantation (Xenotransplantation)
1 Therapies and Procedures and 1 more articles analyzed in the Research Interface, order at left...

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