2- O- (6- O- glycero- manno- heptopyranosyl- glucopyranosyl)glucopyranose

constituent of the outer-core region of the lipopolysaccharide from E coli K-12, indicating the heptosyl residue to be linked to the terminal glucopyranose residue; structure given in first source; RN given refers to (alpha-D-manno-alpha-D-gluco-alpha-D-gluco)-isomer

Also Known As:

2-O-(6-O-L-glycero-alpha-D-manno-heptopyranosyl-alpha-D-glucopyranosyl)-alpha-D-glucopyranose; 2-O-(6-O-glycero-manno-heptopyranosyl-glucopyranosyl)glucopyranose, (alpha-D-manno-alpha-D-gluco-beta-D-gluco)-isomer; 2-O-(6-O-glycero-manno-heptopyranosyl-glucopyranosyl)glucopyranose, (beta-D-manno-alpha-D-gluco-alpha-D-gluco)-isomer; 2-O-(6-O-glycero-manno-heptopyranosyl-glucopyranosyl)glucopyranose, (beta-D-manno-alpha-D-gluco-beta-D-gluco)-isomer; MHGG

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - Oligosaccharides: 3566
    - Trisaccharides: 123
      - 2-O-(6-O-glycero-manno-heptopyranosyl-glucopyranosyl)glucopyranose: 3

Experts

1.	Fu, Xiaodan: 1 article (01/2019)
2.	Li, Meng: 1 article (01/2019)
3.	Li, Rong: 1 article (01/2019)
4.	Mou, Haijin: 1 article (01/2019)
5.	Zhang, Tan: 1 article (01/2019)
6.	Aronow, Bruce: 1 article (01/2016)
7.	Brudno, Michael: 1 article (01/2016)
8.	Buczkowicz, Pawel: 1 article (01/2016)
9.	Chow, Lionel: 1 article (01/2016)
10.	DeWire, Mariko: 1 article (01/2016)

Related Diseases

1.	Constipation 01/01/2019 - "This study suggested that MHGG treatment could elicit constipation relief in mice. " 01/01/2019 - "The aim of this study was to evaluate the effects of high- (HHGG, Mw 10,000-30,000 Da) and medium-molecular-weight (MHGG, Mw 2,000-10,000 Da) partially hydrolyzed guar gum (PHGG) on modulation of gut microbiota and relief of constipation in mice. "
2.	Neoplasms (Cancer) 01/04/2016 - "Diffuse intrinsic pontine glioma (DIPG) and midline high-grade glioma (mHGG) are lethal childhood brain tumors. Spatial genomic heterogeneity has been well-described in adult HGG but has not been comprehensively characterized in pediatric HGG. We performed whole exome sequencing on 38-matched primary, contiguous, and metastatic tumor sites from eight children with DIPG (n = 7) or mHGG (n = 1) collected using a unique MRI-guided autopsy protocol. "
3.	Glioma (Gliomas) 01/04/2016 - "Diffuse intrinsic pontine glioma (DIPG) and midline high-grade glioma (mHGG) are lethal childhood brain tumors. Spatial genomic heterogeneity has been well-described in adult HGG but has not been comprehensively characterized in pediatric HGG. We performed whole exome sequencing on 38-matched primary, contiguous, and metastatic tumor sites from eight children with DIPG (n = 7) or mHGG (n = 1) collected using a unique MRI-guided autopsy protocol. "
4.	Brain Neoplasms (Brain Tumor) 01/04/2016 - "Diffuse intrinsic pontine glioma (DIPG) and midline high-grade glioma (mHGG) are lethal childhood brain tumors. Spatial genomic heterogeneity has been well-described in adult HGG but has not been comprehensively characterized in pediatric HGG. We performed whole exome sequencing on 38-matched primary, contiguous, and metastatic tumor sites from eight children with DIPG (n = 7) or mHGG (n = 1) collected using a unique MRI-guided autopsy protocol. "
5.	Arthritis (Polyarthritis) 02/01/1984 - "Using mice immunized with both mBSA and methylated HGG (mHGG) with either mBSA or mHGG-induced arthritis, we could show that 4-6 weeks after arthritis induction the flare-up phenomenon is antigen specific. "

Related Drugs and Biologics

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2.	Antigens
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4.	methylated bovine serum albumin (MBSA)