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7- nitrobenz- 2- oxa- 1,3- diazol- 4- ylcholesterol

Also Known As:

NBD-cholesterol

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Jiefang: 1 article (01/2021)
2.	Dang, Yiping: 1 article (01/2021)
3.	Guo, Xiaoqing: 1 article (01/2021)
4.	He, Hui: 1 article (01/2021)
5.	He, Quanwei: 1 article (01/2021)
6.	Hu, Bo: 1 article (01/2021)
7.	Hu, Yu: 1 article (01/2021)
8.	Jin, Huijuan: 1 article (01/2021)
9.	Li, Yanan: 1 article (01/2021)
10.	Li, Yuanyuan: 1 article (01/2021)

Related Diseases

1.	Glioblastoma (Glioblastoma Multiforme) 07/01/2008 - "For all measurements in this study, either human glioblastoma cells incubated with the fluorescent membrane marker NBD-cholesterol or human breast cancer cells expressing a membrane-associating fluorescent protein were used."
2.	Breast Neoplasms (Breast Cancer) 07/01/2008 - "For all measurements in this study, either human glioblastoma cells incubated with the fluorescent membrane marker NBD-cholesterol or human breast cancer cells expressing a membrane-associating fluorescent protein were used."
3.	Tics (Tic) 01/01/2021 - ": 2-MeSAMP: 2-methylthioadenosine 5'-monophosphate; 8-CPT-cAMP: 8-(4-chlorophenylthio)-adenosine-3',5'-cyclic-monophosphate; ABCA1: ATP binding cassette subfamily A member 1; ABCG1: ATP binding cassette subfamily G member 1; ACTB: actin beta; ADPβs: adenosine 5'-(alpha, beta-methylene) diphosphate; ALs: autolysosomes; AMPK: AMP-activated protein kinase; APOA1: apolipoprotein A1; APs: autophagosomes; ATG5: autophagy related 5; ATV: atorvastatin; AVs: autophagic vacuoles; CD: chow diet; CDL: clopidogrel; CQ: chloroquine; DAPI: 4',6-diamidino-2-phenylindole; dbcAMP: dibutyryl-cAMP; DIL-oxLDL: dioctadecyl-3,3,3,3-tetramethylin docarbocyanine-oxLDL; EIF4EBP1/4E-BP1: eukaryotic translation initiation factor 4E binding protein 1; EVG: elastic van gieson; HE: hematoxylin-eosin; HDL: high-density lipoprotein; HFD: high-fat diet; KEGG: Kyoto Encyclopedia of Genes and Genomes; LDL-c: low-density lipoprotein cholesterol; LDs: lipid droplets; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; Masson: masson trichrome; MCPT: maximal carotid plaque thickness; MK2206: MK-2206 2HCL; NBD-cholesterol: 22-(N-[7-nitrobenz-2-oxa-1,3-diazol-4-yl] amino)-23,24-bisnor-5-cholen-3β-ol; OLR1/LOX-1: oxidized low density lipoprotein receptor 1; ORO: oil Red O; ox-LDL: oxidized low-density lipoprotein; SQSTM1/p62: sequestosome 1; TEM: transmission electron microscopy; TIC: ticagrelor; ULK1: unc-51 like autophagy activating kinase 1; VSMCs: vascular smooth muscle cells."
4.	Peritonitis 01/01/2014 - "It has to shown that CHL against a background of inflammation promoted reduction of fluorescent NBD-cholesterol efflux from macrophages throughout the studied period (5 days) whereas zymosan inhibited cholesterol efflux at the early stages of inflammation (1 and 2 days), then, on 3ed day, the cholesterol efflux was recovered and increased on day 5. At the same time CHL stimulated the production of TNFα and TGFβ and inhibited the production of IL-10 and DNA-binding activity of PPAR-γ macrophages obtained at early as well as late stages of zymosan-induced peritonitis (compared with injection zymosan only). "
5.	Inflammation (Inflammations) 01/01/2014 - "It has to shown that CHL against a background of inflammation promoted reduction of fluorescent NBD-cholesterol efflux from macrophages throughout the studied period (5 days) whereas zymosan inhibited cholesterol efflux at the early stages of inflammation (1 and 2 days), then, on 3ed day, the cholesterol efflux was recovered and increased on day 5. At the same time CHL stimulated the production of TNFα and TGFβ and inhibited the production of IL-10 and DNA-binding activity of PPAR-γ macrophages obtained at early as well as late stages of zymosan-induced peritonitis (compared with injection zymosan only). "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	AMP-Activated Protein Kinases
3.	Class E Scavenger Receptors (Lectin Like Oxidized Low Density Lipoprotein Receptor 1)
4.	Peroxisome Proliferator-Activated Receptors (PPAR)
5.	Interleukin-10 (Interleukin 10)
6.	Apolipoprotein A-I (Apolipoprotein A1)
7.	Zymosan
8.	Diphosphates (Pyrophosphates)
9.	Peptide Initiation Factors (Initiation Factor)
10.	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)