HLA-B45 antigen

HLA-B44 & HLA-B45 are two distinct serologically defined subtypes of HLA-B12

Also Known As:

HLA B45; HLA B45 antigen; HLA-B45

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        HLA-B Antigens: 1869
        HLA-B45 antigen: 5
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        HLA-B Antigens: 1869
        HLA-B45 antigen: 5
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        HLA-B Antigens: 1869
        HLA-B45 antigen: 5
Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-B Antigens: 1869
        HLA-B45 antigen: 5
      - Histocompatibility Antigens Class I: 1944
        HLA-B Antigens: 1869
        HLA-B45 antigen: 5
  - Isoantigens: 1221
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-B Antigens: 1869
        HLA-B45 antigen: 5
      - Histocompatibility Antigens Class I: 1944
        HLA-B Antigens: 1869
        HLA-B45 antigen: 5

Experts

1.	Flaherty, Lawrence E: 1 article (04/2002)
2.	Kempf, Raymond A: 1 article (04/2002)
3.	Liu, P-Y: 1 article (04/2002)
4.	Park, Min S: 1 article (04/2002)
5.	Sondak, Vernon K: 1 article (04/2002)
6.	Sosman, Jeffrey A: 1 article (04/2002)
7.	Southwest Oncology Group: 1 article (04/2002)
8.	Terasaki, Paul I: 1 article (04/2002)
9.	Thompson, John A: 1 article (04/2002)
10.	Unger, Joseph M: 1 article (04/2002)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 01/01/2001 - "MART-1 is a good candidate antigen for immunotherapy against HLA-A2 patients with melanoma, since it is a highly immunogenic antigen recognized by HLA-A2 and HLA-B45 restricted CD8+ cytotoxic T cells and expressed in the majority of melanoma lesions. " 04/15/2002 - "An association between expression of > or = two of five HLA class I antigens (HLA-A2, HLA-A28, HLA-B44, HLA-B45, and HLA-C3; collectively called M5) and response to an allogeneic melanoma vaccine (Melacine; Corixa Corporation, Seattle, WA) has been described in stage IV melanoma. "
2.	Opportunistic Infections (Opportunistic Infection) 01/01/1995 - "HLA-B45, -B49, and -B50 were each found at a moderately increased frequency among individuals responding to HIV-1 infection with a marked circulating and infiltrative CD8 T-cell lymphocytosis, a slow rate of CD4 T-cell decline, very low frequency of opportunistic infections, and low viral strain heterogeneity. "
3.	Neoplasms (Cancer) 09/01/1987 - "The frequency of HLA-B8, HLA-DR3, and HLA-DQW2 in patients with multiple primary tumors and of HLA-B8, and HLA-B45 in patients with a single head and neck cancer increased significantly as compared with the control population. "
4.	Lymphocytosis 01/01/1995 - "Placing HLA-B45, -B49, and -B50 into one structurally defined group revealed a much stronger and statistically significant association with the CD8 lymphocytosis syndrome (OR = 5.3, p = 0.0005). " 01/01/1995 - "HLA-B45, -B49, and -B50 were each found at a moderately increased frequency among individuals responding to HIV-1 infection with a marked circulating and infiltrative CD8 T-cell lymphocytosis, a slow rate of CD4 T-cell decline, very low frequency of opportunistic infections, and low viral strain heterogeneity. "
5.	Infections 01/01/1995 - "HLA-B45, -B49, and -B50 were each found at a moderately increased frequency among individuals responding to HIV-1 infection with a marked circulating and infiltrative CD8 T-cell lymphocytosis, a slow rate of CD4 T-cell decline, very low frequency of opportunistic infections, and low viral strain heterogeneity. "

Related Drugs and Biologics

1.	HLA-B44 Antigen
2.	HLA-DR3 Antigen (HLA DR3 Antigen)
3.	HLA-B8 Antigen (HLA B8 Antigen)
4.	HLA-A2 Antigen (HLA A2 Antigen)
5.	Histocompatibility Antigens Class I
6.	Vaccines
7.	Antigens
8.	Melacine
9.	HLA-A28 antigen
10.	HLA-B12 antigen

Related Therapies and Procedures

1.	Immunotherapy