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4,8- dihydro- 4- hydroxy- 8- oxo- 2'- deoxyguanosine
structure given in first source; RN given refers to the (4S)-isomer
Also Known As:
4,8-dihydro-4-hydroxy-8-oxo-2'-deoxyguanosine, (4S)-isomer; 4-OH-8-O-2'dG
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purine Nucleosides: 360
Guanosine: 1156
Deoxyguanosine: 166
4,8-dihydro-4-hydroxy-8-oxo-2'-deoxyguanosine: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Purine Nucleosides: 360
Guanosine: 1156
Deoxyguanosine: 166
4,8-dihydro-4-hydroxy-8-oxo-2'-deoxyguanosine: 2
Deoxyribonucleosides: 34
Deoxyguanosine: 166
4,8-dihydro-4-hydroxy-8-oxo-2'-deoxyguanosine: 2
Related Diseases
1.
Photosensitivity Disorders (Photodermatitis)
07/25/1995 - "
The primary products of the methylene blue-mediated photosensitization of 8-oxodG are 2-amino-5-((2-deoxy-beta-D-erythro-pentofuranosyl)amino)-4H-imidazol-4-o ne (dIz), 2,2-diamino-4-((2-deoxy-beta-D-erythro-pentofuranosyl)amino)-5(2H)-oxazo lone (dZ), the 4R* and 4S* diastereoisomers of 4,8-dihydro-4-hydroxy-8-oxo-2'-deoxyguanosine (dO), and an as yet unidentified product with a molecular weight of 287 (dX).
"
09/25/1992 - "
Phthalocyanine mediated photosensitization of 2'-deoxyguanosine (dG) in oxygen saturated aqueous solution has previously been shown to result in the addition of molecular oxygen to the guanine base generating the 4R* and 4S* diastereoisomers of 4,8-dihydro-4-hydroxy-8-oxo-2'-deoxyguanosine (dO) (the asterisk denotes unambiguous assignment of the 4R and 4S diastereoisomers).
"
Related Drugs and Biologics
1.
Solutions
2.
Oxygen (Dioxygen)
3.
Methylene Blue (Methylthioninium Chloride)
4.
Guanine
5.
8-Hydroxy-2'-Deoxyguanosine
6.
phthalocyanine