FK 453

adenosine A1 receptor antagonist; structure given in first source; a new antihypertensive agent with diuretic action in isolated rabbit aorta; FR113452 is the S-(-) enantiomer of FK 453

Also Known As:

(+)-(R)-(1-(E)-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)acryl)-2-piperidine ethanol; FR 113452; FR 113453; FR113452; FR113453; 2-Piperidineethanol, 1-(1-oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-propenyl)-, (R-(E))-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - FK 453: 1
  - Pyridines: 88
    - FK 453: 1

Related Diseases

1.	Acute Kidney Injury (Acute Renal Failure) 01/01/1993 - "The adenosine A1 receptor antagonist (FR113453) prevents glycerol- but not mercury-induced acute renal failure. "

Related Drugs and Biologics

1.	Adenosine A1 Receptor
2.	Mercury
3.	Glycerol (Glycerine)