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nitisinone (Orfadin)

used in treatment of hereditary tyrosinaemia type I
Also Known As:
Orfadin; 2-(2-nitro-4-(trifluoromethyl)benzoyl)cyclohexane-1,3-dione; 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione; NTBC cpd; Orphan Brand of Nitisinone
Networked: 46 relevant articles (7 outcomes, 7 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Ranganath, Lakshminarayan R: 4 articles (09/2015 - 01/2014)
2. Gallagher, James A: 3 articles (09/2015 - 01/2014)
3. McKiernan, P J: 3 articles (08/2015 - 02/2006)
4. Gahl, William A: 3 articles (10/2011 - 06/2005)
5. Hughes, Andrew T: 2 articles (09/2015 - 01/2015)
6. Milan, Anna M: 2 articles (09/2015 - 01/2015)
7. Bussières, Jean-François: 2 articles (05/2015 - 09/2012)
8. Barshop, Bruce A: 2 articles (03/2015 - 01/2015)
9. Gertsman, Ilya: 2 articles (03/2015 - 01/2015)
10. Nyhan, William L: 2 articles (03/2015 - 01/2015)

Related Diseases

1. Tyrosinemias (Tyrosinemia)
2. Alkaptonuria
3. Hepatocellular Carcinoma (Hepatoma)
4. Photophobia (Light Sensitivity)
5. Rickets (Rachitis)

Related Drugs and Biologics

1. Tyrosine (L-Tyrosine)
2. Homogentisic Acid
3. Phenylalanine (L-Phenylalanine)
4. Acids
5. succinylacetone
6. 4-Hydroxyphenylpyruvate Dioxygenase
7. nitisinone (Orfadin)
8. 4-hydroxyphenylpyruvic acid
9. Dioxygenases
10. Biological Markers (Surrogate Marker)

Related Therapies and Procedures

1. Transplants (Transplant)
2. Protein-Restricted Diet (Diet, Protein Restricted)
3. Liver Transplantation