human PRMT2 protein

RefSeq NM_001535

Also Known As:

PRMT2 protein, human; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1 protein, human; HMT1 protein, human; HRMT1L1 protein, human; HRMT1L2; arginine methyltransferase; protein arginine methyltransferase 2, human

Networked: 64 relevant articles (0 outcomes, 6 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - One-Carbon Group Transferases
      - Methyltransferases: 5778
        Protein Methyltransferases: 69
        Protein-Arginine N-Methyltransferases: 359
        human PRMT2 protein: 64
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - human PRMT2 protein: 64
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - human PRMT2 protein: 64

Experts

1.	Zhang, Baolai: 4 articles (01/2022 - 09/2015)
2.	Wu, Yongjie: 2 articles (01/2022 - 09/2015)
3.	Liu, Li-Ming: 2 articles (08/2021 - 01/2019)
4.	Xu, Jian: 2 articles (11/2020 - 01/2018)
5.	Chen, Xue: 2 articles (08/2018 - 12/2017)
6.	Zhang, Su: 2 articles (08/2018 - 12/2017)
7.	Wang, Xing: 2 articles (01/2018 - 12/2017)
8.	Bedford, Mark T: 2 articles (12/2017 - 06/2011)
9.	Shechter, David: 2 articles (06/2015 - 01/2013)
10.	Cavarelli, Jean: 2 articles (09/2014 - 06/2011)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 01/01/2019 - "SIGNIFICANCE: This study provides novel mechanistic insight of the role of the arginine methyltransferase PRMT1 in breast cancer pathogenesis." 10/01/2021 - "Arginine methyltransferase PRMT5 methylates and stabilizes KLF5 via decreasing its phosphorylation and ubiquitination to promote basal-like breast cancer." 08/05/2021 - "Arginine Methyltransferase PRMT1 Regulates p53 Activity in Breast Cancer." 04/12/2016 - "Arginine methyltransferase inhibitor 1 (AMI-1) was used to pharmacologically block PRMT1 in resistant breast cancer cells (MCF7/adr). " 01/01/2020 - "Arginine methyltransferase PRMT7 is associated with human breast cancer metastasis. "
2.	Lung Neoplasms (Lung Cancer) 01/01/2022 - "In this study, we find that the arginine methyltransferase PRMT5 interacts with and methylates Mxi1, which promotes the binding of the β-Trcp ligase to Mxi1, facilitating the ubiquitination and degradation of Mxi1 in lung cancer. " 02/08/2019 - "The arginine methyltransferase PRMT5 and PRMT1 distinctly regulate the degradation of anti-apoptotic protein CFLARL in human lung cancer cells."
3.	Colonic Neoplasms (Colon Cancer) 04/01/2009 - "In this study, the possible relation of the expression pattern of arginine methyltransferase 1 and colon cancer progression is investigated. " 04/01/2009 - "Colon cancer samples as well as normal colon samples were used to define the arginine methyltransferase 1 expression by RT-PCR. " 03/01/2019 - "Downregulation of PRMT1, a histone arginine methyltransferase, by sodium propionate induces cell apoptosis in colon cancer."
4.	Chromosomal Instability (Chromosome Stability) 12/01/2016 - "Immunofluorescent studies of the endothelial cells replication pattern by 5-ethynyl-2'-deoxyuridine incorporation disclosed that AMI-5, and the arginine methyltransferase inhibitor AMI-1, induced heterochromatin formation and a number of nuclear abnormalities, such as formation of micronuclei (MNs) and nucleoplasmic bridges (NPBs), which are markers of chromosomal instability. "
5.	Alcoholic Fatty Liver 12/01/2021 - "This study aimed to probe the function of microRNA-181b-5p (miR-181b-5p)/protein inhibitor of activated STAT1 (PIAS1)/protein arginine methyltransferase 1 (PRMT1) axis in the progression of alcoholic fatty liver disease (AFLD). "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Protein Inhibitors of Activated STAT
3.	Ligases (Synthetase)
4.	Heterochromatin
5.	Cisplatin (Platino)
6.	Antineoplastic Agents (Antineoplastics)
7.	5-ethynyl-2'-deoxyuridine
8.	coactivator-associated arginine methyltransferase 1
9.	Histones (Histone)
10.	Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)

Related Therapies and Procedures

1.	Therapeutics