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pivaloyl-S-(N'-acetylalanyl)-cysteine ethyl ester

an analog of SPM 5185 that lacks the NO moiety

Also Known As:

SPM 5267; SPM-5267

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - pivaloyl-S-(N'-acetylalanyl)-cysteine ethyl ester: 1

Related Diseases

1.

Myocardial Ischemia (Ischemic Heart Diseases)

09/01/1992 - "In the myocardial ischemia (MI)+SPM-5267 group, 38 +/- 4% of the area at risk was necrotic, whereas the necrotic area/area at risk was only 7 +/- 2% in the MI+SPM-5185 group (P less than 0.01). "
09/01/1992 - "Intravenous administration of SPM-5185 [N-nitratopivaloyl-S-(N'-acetylalanyl)-cysteine ethyl ester], a cysteine-containing nitric oxide (NO) donor, or SPM-5267 [pivaloyl-S-(N'-acetylalanyl)-cysteine ethyl ester], an analogue of SPM-5185 that lacks the NO moiety, was studied in a feline myocardial ischemia-reperfusion model. "

Related Drugs and Biologics

1.	pivaloyl-S-(N'-acetylalanyl)-cysteine ethyl ester
2.	Nitric Oxide (Nitrogen Monoxide)
3.	Cysteine (L-Cysteine)
4.	N- nitratopivaloyl- S- (N'- acetylalanyl)- cysteine ethyl ester

Related Therapies and Procedures

1.	Intravenous Administration