centractin

amino acid sequence for both human and dog contractin given in first source; a vertebrate actin-like protein; MW about 43 kDa; alpha & beta are isoforms

Also Known As:

actin-RPV; actin-related protein, RPV; alpha-centractin; beta-centractin; canine centractin; human centractin

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - Biopolymers: 773
    - Microfilament Proteins: 486
      - Actins: 2672
        centractin: 5
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Cytoskeletal Proteins: 739
    - Microfilament Proteins: 486
      - Actins: 2672
        centractin: 5
  - Contractile Proteins: 699
    - Muscle Proteins: 1582
      - Actins: 2672
        centractin: 5

Experts

1.	Fan, Jia: 2 articles (02/2008 - 08/2007)
2.	Gao, Qiang: 2 articles (02/2008 - 08/2007)
3.	Martel, An: 1 article (12/2019)
4.	Pasmans, Frank: 1 article (12/2019)
5.	Verbrugghe, Elin: 1 article (12/2019)
6.	He, Minyi: 1 article (10/2010)
7.	Liu, Yawei: 1 article (10/2010)
8.	Peng, Kang: 1 article (10/2010)
9.	Sun, Xuegang: 1 article (10/2010)
10.	Zhao, Liang: 1 article (10/2010)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 02/01/2008 - "Down-regulation of beta-centractin might be involved in dendritic cells dysfunction and subsequent hepatocellular carcinoma immune escape: a proteomic study." 08/07/2007 - "To investigate the relation between the changes of dendritic cell (DC) function and down-regulation of beta-centractin in hepatocellular carcinoma. " 08/07/2007 - "[Relation between changes of dendritic cell function and down-regulation of beta-centractin in hepatocellular carcinoma]."
2.	Skin Diseases (Skin Disease) 12/06/2019 - "We here present a study screening commonly used reference genes (TEF1F, α-centractin, Ctsyn1, GAPDH, R6046, APRT and TUB) in the chytrid fungi Batrachochytrium dendrobatidis (Bd) and Batrachochytrium salamandrivorans (Bsal), which cause the lethal amphibian skin disease chytridiomycosis. "
3.	Neoplasms (Cancer) 02/01/2008 - "The clinical significance of beta-centractin, one of the largest quantitative changed spot, down-regulation in DCs was further evaluated in autologous PBMCs derived DCs pulsed with auto-tumor lysates in 26 HCC patients. "
4.	Neoplasm Metastasis (Metastasis) 10/01/2010 - "The results revealed that exposure to mild-H₂O₂ for 12 h cause up-regulated expression of DJ-1, glutathione S-transferase P 1, DNA ligase I, dynamin 2, nucleophosmin, and down-regulated expression of nucleoside diphosphate kinase A, enolase-α, barrier-to-autointegration factor 1, metastasis associated protein 1, glycosytransferase-like domain containing protein 1, synaptonemal complex protein 1, alpha-centractin, bromodomain, and PHD finger containing 1 (BRPF1). "
5.	Down Syndrome (Down's Syndrome) 02/15/2002 - "Aberrant expression of centractin and capping proteins, integral constituents of the dynactin complex, in fetal down syndrome brain."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	NM23 Nucleoside Diphosphate Kinases
3.	Dynamin II
4.	Phosphopyruvate Hydratase (Enolase)
5.	Glutathione Transferase (Glutathione S-Transferase)
6.	Nucleophosmin
7.	DNA Ligase ATP
8.	Dynactin Complex