|1.||Zhou, Jun: 4 articles (04/2014 - 03/2012)|
|2.||Li, Dengwen: 4 articles (04/2014 - 03/2012)|
|3.||Sun, Xiaodong: 4 articles (04/2014 - 03/2012)|
|4.||Liu, Min: 4 articles (04/2014 - 03/2012)|
|5.||Lu, Fan: 4 articles (02/2007 - 08/2002)|
|6.||Dong, Bin: 3 articles (04/2014 - 03/2012)|
|7.||Xie, Songbo: 2 articles (04/2014 - 03/2014)|
|8.||Lu, Zifan: 2 articles (05/2006 - 06/2005)|
|9.||Wang, Ruihua: 2 articles (05/2006 - 06/2005)|
|10.||Zhao, Zhongliang: 2 articles (06/2005 - 08/2002)|
04/01/2013 - "These findings thus demonstrate a critical role for CLIP-170 in tumor angiogenesis and suggest its potential as a novel antiangiogenic target."
05/19/2006 - "Our evidence supported that STAT-1alpha plays an important role in the atRA-induced transcriptional up-regulation of restin, which was associated with the atRA-induced HL60 cell differentiation and potentially mediated the downstream effects of atRA signal pathway via STAT-1alpha in some cancer cells."
09/01/2002 - "These results indicated that the expressed restin in vivo could suppress the growth of tumor, and this suppression might be achieved by restraining angiogenesis since the restin had no effect on the proliferation of tumor cells. "
09/01/2002 - "The growth of tumors formed by cells transfected with restin gene was much slower than that of control group. "
09/01/2002 - "[Restin expressed in vivo suppresses the growth of tumors in nude mice]."
|2.||Hodgkin Disease (Hodgkin's Disease)
12/15/1998 - "Surprisingly, NNX3 was immunochemically detected in Reed-Sternberg cells of Hodgkin disease, in parallel with restin, a cytoplasmic protein we previously characterized (J. "
01/01/1994 - "Localization of the gene (RSN) coding for restin, a marker for Reed-Sternberg cells in Hodgkin's disease, to human chromosome band 12q24.3 and YAC cloning of the locus."
12/01/1992 - "However, Restin was present in Reed-Sternberg cells and variants thereof in Hodgkin's disease, with the exception of the lymphocyte-predominant, paragranuloma subtype. "
06/01/1992 - "We suggest that restin overexpression may be a contributing factor in the progression of Hodgkin's disease."
06/01/1992 - "In a survey of normal, inflammatory and human tumour tissue samples, this protein, which we have named restin, was found to be highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. "
|3.||Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
06/25/2008 - "Scratching altered the associations of IQGAP1 with β-catenin, adenomatous polyposis coli (APC) and cytoplasmic linker protein-170 (CLIP-170). "
01/01/2005 - "Linkage of microtubule plus ends to the cortical region is essential for polarized migration. +TIPs, including CLIP-170 and APC (adenomatous polyposis coli) are thought to function as capturing devices at specialized cortical regions. "
02/19/2010 - "Fluorescence spectroscopy and nuclear magnetic resonance studies in the presence of the cytoskeleton-associated protein-glycine-rich domains of either CLIP-170 or p150(glued) or of a fragment derived from the adenomatous polyposis coli tumor suppressor protein show that chain exchange of EBc domains can be controlled by binding partners. "
11/01/2015 - "cerevisiae kinesin Kip2 stabilises astral microtubules (MTs) and facilitates spindle positioning through transport of MT-associated proteins, such as the yeast CLIP-170 homologue Bik1, dynein and the adenomatous-polyposis-coli-related protein Kar9 to the plus ends of astral MTs. "
|4.||Melanoma (Melanoma, Malignant)
06/01/2005 - "Restin, a member of melanoma-associated antigen superfamily gene, was first cloned from differentiated leukemia cell induced by all trans-retinoic acid, and was able to inhibit cell proliferation, but the molecular mechanism was not clear. "
08/01/2002 - "In the present study, a new member of melanoma associated antigens (Mage), named Restin (219 amino acids), was identified from HL-60 cell induced by all-trans-retinoic acid (ATRA) by PCR-based subtractive hybridization. "
02/01/2007 - "Restin, belonging to the melanoma-associated antigen superfamily, was firstly cloned from the differentiated HL-60 cells when induced by all-trans retinoic acid (ATRA) in our lab. "
05/19/2006 - "RESTIN, a member of the melanoma-associated antigen superfamily, is a nuclear protein induced by atRA (all-trans retinoic acid) in HL60 cells. "
|5.||Breast Neoplasms (Breast Cancer)
01/01/2015 - "Our study was performed to detect if Restin plays a role in breast cancer cells in vitro and in vivo. "
01/01/2015 - "Real-time PCR and western blot were conducted to detect Restin expression in multiple breast cancer cell lines and Restin level was negatively related with cell motility. "
04/04/2008 - "Regulation of lamellipodia formation and cell invasion by CLIP-170 in invasive human breast cancer cells."
04/01/2013 - "Depletion of CLIP-170 significantly impaired vascular endothelial tube formation and sprouting in vitro and inhibited breast tumor growth in mice by decreasing tumor vascularization. "
04/01/2013 - "Herein, we show that the microtubule-binding protein CLIP-170 (cytoplasmic linker protein of 170 kDa) is highly expressed in breast tumor samples and correlates positively with blood vessel density. "
|1.||Tretinoin (Retinoic Acid)
|2.||Proteins (Proteins, Gene)
|5.||Glycine (Aminoacetic Acid)
|7.||Collagen Type XVIII (Type XVIII Collagen)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)