Chloramphenicol FDA Link

An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)

Also Known As:

Chloromycetin; Chlornitromycin; Ophthochlor; Cloranfenicol; Kloramfenikol; Amphenicol; Amphenicols; Chlorocid; Detreomycin; Syntomycin; Levomycetin; Acetamide, 2,2- dichloro- N- (2- hydroxy- 1- (hydroxymethyl)- 2- (4- nitrophenyl)ethyl)- , (R-(R*,R*))-

Pharmalogical Action Categories:

Anti-Bacterial Agents
Protein Synthesis Inhibitors

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Nitrobenzenes: 7
        Chloramphenicol: 3903
- Alcohols: 595
  - Glycols: 38
    - Propylene Glycols: 2
      - Chloramphenicol: 3903
- Nitro Compounds: 66
  - Nitrobenzenes: 7
    - Chloramphenicol: 3903

1,3-diacetylchloramphenicol

Bio-Agent Context: Research Results