|1.||Hashimoto, Takashi: 13 articles (10/2015 - 11/2003)|
|2.||Zillikens, Detlef: 9 articles (03/2013 - 06/2002)|
|3.||Auer, G: 8 articles (11/2005 - 01/2001)|
|4.||Schmidt, Enno: 7 articles (03/2013 - 06/2002)|
|5.||Lazarova, Z: 7 articles (11/2011 - 01/2000)|
|6.||Berndt, Alexander: 7 articles (01/2011 - 01/2003)|
|7.||Kosmehl, Hartwig: 7 articles (01/2011 - 01/2003)|
|8.||Miyazaki, Kaoru: 7 articles (10/2006 - 01/2002)|
|9.||Hirohashi, Setsuo: 7 articles (09/2004 - 01/2002)|
|10.||Ochiai, Atsushi: 6 articles (01/2016 - 01/2004)|
04/01/2000 - "These studies demonstrated that neither complement activation nor cross-linking of laminin 5 in epidermal basement membranes was required for induction of subepidermal blister formation in this animal model of a human autoimmune bullous disease."
08/01/2000 - "Basement membrane components were atypically deposited and, at least in the case of laminin-5, improperly processed, leading to disruption of the basement membrane and blister formation at the dermal-epidermal junction. "
03/01/1998 - "In 4-day-old blisters, about 20-50 cells at the leading edge of the migrating tongue showed cytoplasmic laminin-5 immunostaining. "
12/01/2006 - "The cutaneous biopsy and ultrastructural and immunohistochemical studies showed a subepidermal bulla in the lamina lucida, absence of hemidesmosomes and marked decrease of laminin 5, thus establishing the diagnosis of Bart syndrome associated to the Herlitz form of lethal junctional epidermolysis bullosa. "
05/01/2000 - "Band-like immunostaining in the basement membrane for laminin 5, alpha5 and beta1 chains was continuous in blister bases, but partially discontinuous in open wound bases. "
03/01/2014 - "The aim of this study was to evaluate the expression of laminin-5 γ2 in OSCC and its association with intensity of tumor budding and density of stromal myofibroblasts. "
03/01/2008 - "Further study of other basal-like tumors for laminin 5 expression is warranted to determine the usefulness of laminin 5 in their diagnosis."
03/01/2007 - "Recent studies have shown that laminin-5 (LN-5), a major component of the epithelial basement membrane, plays a more active role in cell migration or tumor invasion. "
04/01/2005 - "Together with previous studies showing that laminin-5 is involved in the invasive and malignant phenotype of several tumor types, our data suggest that the oncogenic effect of EWS-ETS may be mediated in part by upregulation of LAMB3 expression."
02/01/2005 - "In a further study, the degree of budding, which was assessed by an immunohistochemical study of gamma2 chain of laminin-5, was closely related to the number and location of isolated tumor cells. "
|3.||Junctional Epidermolysis Bullosa (Epidermolysis Bullosa Letalis)
01/01/2013 - "Laminin 332 in junctional epidermolysis bullosa."
12/01/2008 - "Deficiency of the basement membrane component laminin-5 (LAM5) causes junctional epidermolysis bullosa (JEB), a severe and often fatal skin adhesion defect. "
06/01/2008 - "Junctional epidermolysis bullosa (JEB) is an inherited mechanobullous disease characterized by reduced adherence of the epidermal keratinocytes to the underlying dermis, and is often caused by the absence of functional laminin 332 due to the lack or dysfunction of its beta3 chain. "
01/01/2008 - "Herlitz junctional epidermolysis bullosa: laminin-5 mutational profile and carrier frequency in the Italian population."
12/01/2007 - "Here, we discuss current understanding of the biological functions of laminin-5, the pathogenic impact of its deficiency and implications on molecular approaches towards a therapy of junctional epidermolysis bullosa."
|4.||Benign Mucous Membrane Pemphigoid (Cicatricial Pemphigoid)
11/01/1995 - "Studies of patients with anti-epiligrin cicatricial pemphigoid."
05/01/2011 - "Anti-epiligrin cicatricial pemphigoid is an autoimmune blistering disorder that has recently been associated with the development of solid organ malignancy. "
01/01/2008 - "Two cases of anti-epiligrin cicatricial pemphigoid with and without associated malignancy."
01/01/2007 - "A subset, known as anti-epiligrin cicatricial pemphigoid is associated with a high risk for malignancy. "
11/01/2006 - "To report an anti-epiligrin cicatricial pemphigoid (AECP) patient with severe ocular involvement and to provide a practical approach to distinguishing AECP patients from those with other subepidermal blistering diseases. "
03/01/2008 - "Thus laminin 5 may be helpful for making the diagnosis of metaplastic carcinomas in biopsies, allowing the potential for aggressive early treatment. "
05/01/2013 - "Hence the study of laminin-5 immunohistologically can be regarded as an adjunct to distinguish severe dysplastic lesions from early oral invasive carcinoma."
01/01/2002 - "The aim of our study was to determine if laminin-5 gamma 2 chain antibody can act as a sensitivity marker of invasive capacity in precancerous and invasive carcinoma in women with uni- and multifocal changes in the anogenital tract. "
10/01/1996 - "Although it is unclear how the gene for the gamma 2 subchain of laminin 5 is regulated, results of this study suggest that there is a post-transcriptional defect in the expression of the gamma 2 subchain that occurs during the progression from a premalignant lesion to invasive carcinoma. "
07/01/2015 - "LamC2 and kalinin B1 expression was seen in 28 of 36 (77.8%) and 26 of 36 (72.2%) metaplastic carcinomas, respectively. "
|4.||Eosine Yellowish-(YS) (Eosin)
|5.||Matrix Metalloproteinase 7 (Matrilysin)
|6.||DNA (Deoxyribonucleic Acid)
|2.||Drug Therapy (Chemotherapy)