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Meldrum's acid

structure given in first source

Also Known As:

2,2-dimethyl-1,3-dioxane-4,6-dione; cyclic isopropylidene malonate

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Dioxanes
    - Meldrum's acid: 3

Experts

1.	Prior, Allan M: 1 article (01/2019)
2.	Sun, Dianqing: 1 article (01/2019)
3.	Herald, Delbert L: 1 article (06/2004)
4.	Hogan, Fiona: 1 article (06/2004)
5.	Pettit, George R: 1 article (06/2004)

Related Diseases

1.	Neoplasms (Cancer) 02/13/2023 - "Vanillidene Meldrum's acid compounds were tested against different cancer cell lines and microbes. " 06/11/2004 - "Subsequent condensation with carboxylic acid 11 (four steps from Meldrum's acid) provided a practical synthesis of the cancer cell growth inhibitor dolastatin 18 (2, Dhex-(S)-Leu-(R)-N-Me-Phe-Doe). "
2.	Tuberculosis (Tuberculoses) 01/14/2019 - "The first total synthesis of diazaquinomycins H (1) and J (2), which are promising anti-tuberculosis natural product leads, has been achieved via selective amidation of diamine 6 with Meldrum's acid derivatives, subsequent EDC coupling with 3-oxobutanoic acid, followed by double Knorr cyclization in the presence of triisopropylsilane (TIPS). "

Related Drugs and Biologics

1.	Growth Inhibitors
2.	Diamines
3.	Carboxylic Acids
4.	Acids
5.	dolastatin 18

Related Therapies and Procedures

1.	Transjugular Intrahepatic Portasystemic Shunt