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pterin-4a-carbinolamine dehydratase

bifunctional protein which converts pterin-4a-carbinolamine to quinoid dihydrobiopterin and functions as dimerization cofactor for HNF-1alpha; deficiency results in an atypical form of phenylketonuria; RefSeq NM_025273 (mouse); NM_000281 (human); NM_001007601 (rat)
Also Known As:
4a-carbinolamine dehydratase; 4a-hydroxytetrahydrobiopterin dehydratase; 4alpha-carbinolamine dehydratase; 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) protein, human; DCoH protein, human; Dcoh protein, mouse; PCBD1 protein, human; Pcbd1 protein, mouse; Pcbd1 protein, rat; PhhB protein, Pseudomonas aeruginosa; dimerization cofactor of HNF-1alpha; dimerization cofactor of hepatic nuclear factor 1-alpha, human; dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1, mouse; dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1, rat; phenylalanine hydroxylase-stimulating protein; phenylalanine hydroxylase-stimulating protein, human; pt-c dehydratase; pterin 4 alpha carbinolamine dehydratase, rat; pterin-4 alpha-carbinolamine dehydratase, human; pterin-4 alpha-carbinolamine dehydratase, mouse; pterin-4alpha-carbinolamine dehydratase
Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Related Diseases

1. Dehydration (Water Stress)
2. Vitiligo
3. Phenylketonurias (Phenylketonuria)
4. Colonic Neoplasms (Colon Cancer)

Related Drugs and Biologics

1. Hepatocyte Nuclear Factor 1
2. Tyrosine (L-Tyrosine)
3. Monophenol Monooxygenase (Tyrosinase)
4. Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)
5. 2- amino- 4- hydroxy- 7- (dihydroxypropyl)- 5,6,7,8- tetrahydrobiopterin
6. 7- (1,2- dihydroxypropyl)- 5,6,7,8- tetrahydrobiopterin