2,3-naphthalocyanine

03/01/1994 - "The possibility of extending photodynamic therapy to the treatment of highly pigmented neoplastic lesions was tested by using Si(IV)-naphthalocyanine (SiNc) as a tumor-localizing agent. "
05/01/2016 - "We demonstrated that the combined near infrared photodynamic and photothermal therapy using the silicon 2,3-naphthalocyanine dihydroxide-loaded gold nanorods exhibit superior efficacy in cancer cell destruction as compared to photodynamic therapy and photothermal therapy alone. "
01/01/1994 - "Pharmacokinetic and tissue distribution studies of the photosensitizer bis(di-isobutyl octadecylsiloxy)silicon 2,3-naphthalocyanine (isoBOSINC) in normal and tumor-bearing rats."
01/01/1996 - "Effect of delivery system on the pharmacokinetics and tissue distribution of bis(di-isobutyl octadecylsiloxy)silicon 2,3-naphthalocyanine (isoBOSINC), a photosensitizer for tumor therapy."
08/23/1991 - "Bis(di-isobutyl octadecylsiloxy)silicon 2,3-naphthalocyanine (isoBOSINC) is a synthetic potential photosensitizer for tumor therapy. "

11/01/1995 - "Photodynamic therapy of ocular melanoma with bis silicon 2,3-naphthalocyanine in a rabbit model."
03/01/1994 - "Photodynamic therapy of B16 pigmented melanoma with liposome-delivered Si(IV)-naphthalocyanine."
01/01/1994 - "A diode laser with roughly 480 mW/cm2 emission at 776 nm was developed and engineered to obtain a uniform illumination of tumour cells deposited on Petri dishes having an external diameter of 5 cm. The efficacy of the apparatus in inducing photocytotoxic effects was successfully checked by irradiation of pigmented melanoma cells in the presence of a photosensitizer, Si(IV)-naphthalocyanine, having intense absorption bands at 776 nm. Our results open interesting prospects for extending photodynamic therapy to highly pigmented tumours. "
02/01/1996 - "59, 362-365, 1994) showed that liposome-delivered Si(IV)-naphthalocyanine (SiNc) photosensitizes B16 pigmented melanoma subcutaneously transplanted in C57 mice to the action of 776 nm light. "
11/01/1995 - "To investigate bis (tri-n-hexylsiloxy) silicon 2,3-naphthalocyanine (SINc; 0.5 mg/kg) for photodynamic therapy of an experimental ocular melanoma in pigmented rabbits. "

10/01/1997 - "A Si(IV)-naphthalocyanine bearing two methoxyethylenglycol axial ligands to the centrally coordinated metal ion (SiNc) was prepared by chemical synthesis and assayed for the phototherapeutic activity after administration in a Cremophor formulation to C57BI/6 mice bearing a subcutaneously transplanted Lewis lung carcinoma or B16 pigmented melanoma. "

03/30/2023 - "Herein, we functionalized semiconducting polymer nanoparticles (SPNs) with cRGD-peptide and silicon 2,3-naphthalocyanine bis(trihexylsilyloxide) (NIR775) to target breast cancer and perform aPTT under an ultra-low laser power (0.2 W cm-2) after breast-conserving surgery (BCS). "