arginine polyamine

at low concentration the compound is an inhibitor of low threshold T-type voltage-activated Ca++ currents; at high concentrations it interacts with ion channels or other membrane constituents to produce a variety of actions on both voltage & ligandgated ion channels

Also Known As:

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Di-Feng: 1 article (01/2018)
2.	Wang, Chaojie: 1 article (01/2018)
3.	Yao, Wen-Jing: 1 article (01/2018)
4.	Zhao, Mei-Xia: 1 article (01/2018)
5.	Zhu, Bing-Jie: 1 article (01/2018)
6.	Gardiner, Donald M: 1 article (08/2009)
7.	Kazan, Kemal: 1 article (08/2009)
8.	Manners, John M: 1 article (08/2009)

Related Diseases

1.	Neoplasms (Cancer) 10/01/1998 - "These observations that NOHA and NO may inhibit sequential steps in the arginine-polyamine pathway suggest a novel biological role for NOS in the inhibition of cell proliferation of certain tumor cells and possibly other cell types." 01/01/2018 - "Especially, the more positively charged β-CD-l-Arg-polyamine-coated CdSe/ZnS QDs could effectively deliver the doxorubicin (Dox) into cells and exhibit excellent cell selectivity in cancer versus normal cells. "
2.	Infections 08/01/2009 - "From this work, we propose that products of the arginine-polyamine biosynthetic pathway in plants may play a role in the induction of trichothecene biosynthesis during infection."

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	trichothecene