luffariellolide

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3 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Description: structure given in first source; a partially reversible phospholipase A2 inhibitor; a major metabolite of the sponge Luffariella; do not confuse with luffolide, a minor metabolite of the same species

Also Known As:

2(5H)-Furanone, 4-(4,8-dimethyl-10-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3,7-decadienyl)-5-hydroxy-, (E,E)-

Bio-Agent Context: Research Results

Organic Chemicals: 40

Hydrocarbons: 382

Terpenes: 149

luffariellolide: 3

Related Diseases

1.	Edema 06/01/1989 - "The PLA2 inhibitors, luffariellolide and aristolochic acid, reduced the edema but only when coinjected with the PLA2" 01/01/1995 - "PMA-induced ear edema was effectively inhibited by scalaradial, luffariellolide and aristolochic acid (ED50 = 70, 50 and 50 micrograms/ear, respectively) whereas ellagic acid was less effective (ED50 = 230 micrograms/ear)" Order ALL the reference details at left...
2.	Lymphoma (Lymphomas) 11/01/2004 - "Luffariellolide and its 25-O-methyl congener as well as acantholide E (5) were cytotoxic against the mouse lymphoma L5187Y cell line" Order ALL the reference details at left...
3.	Contact Dermatitis (Eczema, Contact) 01/01/1995 - "In the mouse model of oxazolone contact hypersensitivity, these PLA2 inhibitors have little effect (< or = 30% inhibition at 400 micrograms/ear) with scalaradial and luffariellolide being less effective than either aristolochic or ellagic acid" Order ALL the reference details at left...

Related Drugs and Biologics

1.	aristolochic acid I (aristolochic acid)
2.	Oxazolone
3.	Ellagic Acid
4.	scalaradial
5.	acantholide

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