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cocaine methiodide
does not cross blood barrier; less effective than cocaine on cardiovascular function
Also Known As:
(1R,2R,3S,5S)-3-benzoyloxy-8,8-dimethyl-8-azoniabicyclo(3.2.1)octane-2-carboxylic acid methyl ester iodide; 8-Azoniabicyclo(3.2.1)octane, 3-(benzoyloxy)-2-(methoxycarbonyl)-8,8-dimethyl-, iodide, (1R,2R,3S,5S)- (1:1)
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Aza Compounds: 3
Azabicyclo Compounds
Tropanes: 1
Cocaine: 10317
cocaine methiodide: 2
Heterocyclic Compounds: 198
Alkaloids: 5398
Tropanes: 1
Cocaine: 10317
cocaine methiodide: 2
Bridged-Ring Heterocyclic Compounds
Tropanes: 1
Cocaine: 10317
cocaine methiodide: 2
Heterocyclic Bridged Bicyclo Compounds
Azabicyclo Compounds
Tropanes: 1
Cocaine: 10317
cocaine methiodide: 2
Experts
1.
Booze, R M
: 1 article (05/2000)
2.
Dowell, R T
: 1 article (05/2000)
3.
Mactutus, C F
: 1 article (05/2000)
Related Diseases
1.
Status Epilepticus (Complex Partial Status Epilepticus)
09/01/1992 - "
Infusion of cocaine methiodide (2 mg/kg/min), a quaternary derivative of cocaine, also produced a lethal episode of status epilepticus, but it was 6 times less potent than cocaine on a molar basis.
"
2.
Bradycardia
05/01/2000 - "
The lack of an effect of cocaine methiodide on HR was consistent with the bradycardia effect of cocaine attributable to central mediation of the baroreflex.
"
Related Drugs and Biologics
1.
Cocaine (Cocaine HCl)