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3-nitrosobenzamide
Networked:
5
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Benzamides: 115
3-nitrosobenzamide: 5
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzoates: 426
Benzamides: 115
3-nitrosobenzamide: 5
Carboxylic Acids: 973
Carbocyclic Acids
Benzoates: 426
Benzamides: 115
3-nitrosobenzamide: 5
Nitroso Compounds: 446
3-nitrosobenzamide: 5
Related Diseases
1.
Infections
10/15/1993 - "
The C-nitroso compound 3-nitrosobenzamide, which has been shown to remove zinc from the retroviral-type zinc finger of p7NC nucleocapsid proteins, inhibits acute infection of human immunodeficiency virus type 1 in cultured human lymphocytes.
"
02/04/1993 - "
We show here that two such compounds, 3-nitrosobenzamide and 6-nitroso-1,2-benzopyrone, inhibit infection of human immunodeficiency virus HIV-1 in human lymphocytes and also eject zinc from isoalted HIV-1 nucleocapsid zinc fingers and from intact HIV-1 virions.
"
09/02/1994 - "
Since protease inhibitors and 3-nitrosobenzamide restrict processes relating to steps early in infection, the cleavage of the nucleocapsid protein may represent an essential event that can be exploited for the design of novel antiviral agents.
"
2.
Virus Diseases (Viral Diseases)
07/12/1993 - "
The 3-nitrosobenzamide (NOBA) drug abolishes SIV replication sharply at 20 microM concentration when CEM x 174 cells are preincubated for 1 h with the drug prior to viral infection.
"
3.
Lymphoma (Lymphomas)
09/09/1999 - "
The effect of 3-nitrosobenzamide (NOBA) on the etoposide, staurosporine and dexamethason induced rapid (4-6 hr), caspase-dependent apoptosis was investigated in thymocytes and lymphoma cells by flow cytometric assay of DNA fragmentation.
"
Related Drugs and Biologics
1.
Nucleocapsid Proteins
2.
Zinc
3.
Staurosporine
4.
Protease Inhibitors (Protease Inhibitor)
5.
Etoposide (VP 16)
6.
Antiviral Agents (Antivirals)
7.
6-nitroso-1,2-benzopyrone