calanolide A

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3 relevant articles (0 outcomes, 1 trials/studies) found for this Bio-Agent

Description: NSC 661122 and costatolide are isomers; a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum (Clusiaceae); structure in first source

Also Known As:

NSC 661122; calanolide F; costatolide; 2H,6H,10H-Benzo(1,2-b:3,4-b':5,6-b'')tripyran-2-one, 11,12-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-, (10R-(10alpha,11beta,12alpha))-

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

2-Ring Heterocyclic Compounds

Related Diseases

1.	Infection 11/01/1996 - "Viral life-cycle studies indicated that calanolide A acted early in the infection process, similar to the known HIV reverse transcriptase (RT) inhibitor 2', 3'-dideoxycytidine" Get all the results and reference details, order at left...
2.	HIV Infections (HIV Infection) 09/01/1998 - "Both (+)-calanolide A (Cal A; NSC 675451) and (+)-dihydrocalanolide A (DHCal A; NSC 678323) are currently under development for the treatment of HIV infections" Get all the results and reference details, order at left...
3.	Acquired Immunodeficiency Syndrome (AIDS) 10/01/1998 - "Calanolide A, a novel dipyranocoumarin from the Malesian tree Calophyllum lanigerum var. austrocoriaceum, and a closely related compound, (-)-calanolide B, isolated from Calophyllum teysmannii var. inophylloide, are representatives of a distinct class of nonnucleoside HIV-1 specific reverse-transcriptase inhibitor under development as an AIDS chemotherapeutic" Get all the results and reference details, order at left...
3 Diseases and 3 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	HIV Reverse Transcriptase
2.	RNA-Directed DNA Polymerase (Reverse Transcriptase)
3.	dihydrocalanolide A
4.	calanolide B
4 Drugs and Important Bio-Agents and 3 more articles analyzed in the Research Interface, order at left...

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