2',3'-dideoxy-5-fluoro-3'-thiacytidine

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4 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Description: RN given refers to (2R-cis)-isomer; RN for cpd without isomeric designation not available 2/93

Also Known As:

1-(2-(hydroxymethyl)oxathiolan-5-yl)-5-fluorocytosine; 2',3',5-FTC; 2',3'-dideoxy-5-fluoro-3'-thiacytidine, (2S-cis)-isomer; 5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine; 524W91; BW 524W91; BW-524W91; BW524W91; Racivir

Bio-Agent Context: Research Results

Related Diseases

1.	Infection 07/01/2005 - "Racivir [RCV; (+/-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine], a 50:50 racemic mixture of the two beta nucleoside enantiomers, is currently in development for the treatment of human immunodeficiency virus type 1 (HIV-1) infections" 02/01/1996 - "HBV replication was equally inhibited in cultures incubated with 524W91 when the drug was added 24 h preinfection, at infection, or 24 h postinfection" Order ALL the reference details at left...
2.	Hepatocellular Carcinoma (Hepatoma) 02/01/2001 - "We investigated the replication fitness and susceptibility of the wild-type and five mutant HBVs (L528M, M552I, M552V, L528M/M552I, and L528M/M552V) to 11 compounds [lamivudine, adefovir, entecavir (BMS-200475) (+)-BCH-189 (+/-)-FTC (racivir) (-)-FTC (emtricitabine) (+)-FTC, L-D4FC, L-FMAU (clevudine), D-DAPD, and (-)-carbovir] by transfecting HBV DNA into hepatoma cells and monitoring viral products by Southern blotting" Order ALL the reference details at left...
3.	Body Weight (Weight, Body) 12/01/1994 - "The pharmacokinetics and bioavailability of 524W91 after oral dosing were studied in mice dosed with 10, 100, and 600 mg of 524W91 per kg of body weight by the oral and intravenous routes" Order ALL the reference details at left...

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