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histidinohydroxylysinonorleucine

major cross-link of skin collagen in patients with amyotrophic lateral sclerosis

Also Known As:

HH-Lys-nLeu

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - histidinohydroxylysinonorleucine: 3
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Histidine: 2980
      - histidinohydroxylysinonorleucine: 3
  - Cyclic Amino Acids: 3
    - Histidine: 2980
      - histidinohydroxylysinonorleucine: 3

Experts

1.	Ishikawa, O: 1 article (01/2001)
2.	Tamura, M: 1 article (01/2001)

Related Diseases

1.	Systemic Scleroderma (Systemic Sclerosis) 02/01/1998 - "Mature type of skin collagen crosslink, histidinohydroxylysinonorleucine, is significantly increased in the skin of systemic sclerosis patients."
2.	Localized Scleroderma (Morphea) 01/01/2001 - "An increase of mature type skin collagen cross-link, histidinohydroxylysinonorleucine, in the sclerotic skin of morphea."
3.	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/01/1993 - "The diameter of collagen fibrils and the age-related, stable cross-link, histidinohydroxylysinonorleucine (HHL), of skin tissue (left biceps) were measured and compared in 11 patients with amyotrophic lateral sclerosis (ALS) and 7 controls. "

Related Drugs and Biologics

1.	Collagen