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RU 40555

a potent antiglucocorticoid; differs from mifepristone only by a methyl radical

Also Known As:

RU-40555

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Estranes
      - Estrenes
        Mifepristone: 1726
        RU 40555: 2

Related Diseases

1.	Infections 03/01/1995 - "Sparfloxacin and RU-40555, which exhibited a moderate activity in the model of early infection, were not effective in this model of established infection. " 04/01/1993 - "Efficacy of granulocyte colony-stimulating factor and RU-40555 in combination with clarithromycin against Mycobacterium avium complex infection in C57BL/6 mice."
2.	Body Weight (Weight, Body) 04/01/1993 - "Mice were pretreated daily with clarithromycin (50 mg/kg of body weight subcutaneously [s.c.]), RU-40555 (100 mg/kg s.c.), or granulocyte colony-stimulating factor (G-CSF) at low dose (15 micrograms/kg intraperitoneally [i.p.]) or high dose (300 micrograms/kg i.p.) 3 days before intravenous challenge with 2.5 x 10(7) CFU of the MO-1 strain of M. " 03/01/1995 - "Sparfloxacin (50 mg/kg of body weight), ethambutol (50 mg/kg), minocycline (25 mg/kg), and the inhibitor of the cortisol receptors RU-40555 (100 mg/kg) were compared with clarithromycin (50 mg/kg). "

Related Drugs and Biologics

1.	Clarithromycin (Biaxin)
2.	Granulocyte Colony-Stimulating Factor (G-CSF)
3.	Minocycline (Cyclops)
4.	Ethambutol (Myambutol)
5.	sparfloxacin (AT 4140)
6.	hydrocortisone receptor