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amphiphysin

amino acid sequence given in first source; a 75 kDa acidic protein, associated with synaptic vesicles; from mammalian brain; amphiphysin I & II are isoforms
Also Known As:
amphiphysin 2; amphiphysin I; amphiphysin II; amphiphysin IIm
Networked: 154 relevant articles (0 outcomes, 9 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Laporte, Jocelyn: 19 articles (01/2022 - 09/2007)
2. Cowling, Belinda S: 8 articles (01/2022 - 01/2012)
3. Pittock, Sean J: 8 articles (10/2020 - 07/2005)
4. Kretz, Christine: 7 articles (01/2022 - 09/2007)
5. Toussaint, Anne: 6 articles (11/2020 - 09/2007)
6. Nicot, Anne-Sophie: 6 articles (01/2019 - 09/2007)
7. Lennon, Vanda A: 5 articles (10/2020 - 07/2005)
8. McKeon, Andrew: 5 articles (10/2020 - 12/2009)
9. Prokic, Ivana: 4 articles (11/2020 - 06/2013)
10. Romero, Norma B: 4 articles (01/2019 - 06/2010)

Related Diseases

1. Neoplasms (Cancer)
2. Stiff-Person Syndrome (Stiff Man Syndrome)
3. Breast Neoplasms (Breast Cancer)
4. Congenital Structural Myopathies (Centronuclear Myopathy)
5. Alzheimer Disease (Alzheimer's Disease)
12/01/2023 - "Belonging to the BIN1/amphiphysin/RVS167 (BAR) superfamily, the bridging integrator (BIN1) has been identified to impact two major pathological hallmarks in Alzheimer's disease (AD), i.e., amyloid beta (Aβ) and tau accumulation. "
10/01/2013 - "The bridging integrator 1 (BIN1) gene, also known as amphiphysin 2, has recently been identified as the most important risk locus for late onset Alzheimer's disease (LOAD), after apolipoprotein E (APOE). "
01/01/2022 - "The present study aimed to determine whether peripheral blood neural cell adhesion molecule (NCAM)/amphiphysin 1 dual-labeled exosomal proteins and microRNAs (miRs) might serve as a marker for the early diagnosis of Alzheimer's disease (AD). "
12/01/2009 - "This suggests that amphiphysin I may be an important regulator for SVE when massive amounts of Ca2 flow into presynaptic terminals, a phenomenon observed in neurodegenerative disorders such as ischemia/anoxia, epilepsy, stroke, trauma and Alzheimer's disease. "
10/01/2020 - "AD: Alzheimer's disease; DMPs: Differentially methylated positions; CSF: Cerebrospinal fluid; βA42: β-amyloid 42; PET: positron emission tomography; 5mC: 5-methyl cytosine; CpG: cytosine-guanine dinucleotides; ANK1: ankyrin-1; BIN1: amphiphysin II; p-tau: hyperphosphorylated tau; CERAD: Consortium to Establish A Registry for Alzheimer's Disease; SD: standard deviation; ANOVA: one-way analysis of variance; VLCFAs: very long-chain fatty acids; DHA: docosahexaenoic acid; mTOR: mechanistic target of rapamycin."

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Antibodies
3. Proteome
4. Dynamin II
5. Benzodiazepines
6. Tamoxifen
7. Steroids
8. Casein Kinases (Casein Kinase)
9. MicroRNAs (MicroRNA)
10. Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)

Related Therapies and Procedures

1. Plasmapheresis
2. Immunomodulation
3. Therapeutics
4. Immunotherapy