PF 1022A

structure given in first source; isolated from Mycelia Sterilia

Also Known As:

PF-1022A; PF1022A; cyclo(D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N-methylleucyl-D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N-methylleucyl); Cyclo(D-2-hydroxypropanoyl-N-methyl-L-leucyl-3-phenyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl-3-phenyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl)

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Fraatz, Kristine: 1 article (09/2013)
2.	Harder, Achim: 1 article (09/2013)
3.	Krebber, Ralph: 1 article (09/2013)
4.	Krücken, Jürgen: 1 article (09/2013)
5.	Kulke, Daniel: 1 article (09/2013)
6.	Mehlhorn, Heinz: 1 article (09/2013)
7.	VON Samson-Himmelstjerna, Georg: 1 article (09/2013)
8.	Graeff-Teixeira, Carlos: 1 article (07/2003)
9.	Mentz, Márcia Bohrer: 1 article (07/2003)

Related Diseases

1.	Infections 07/01/2003 - "We review the drug trials in murine experimental models and conclude that most of them could not be considered good candidates for treatment of human infection, except for PF1022A, pyrantel and flubendazole."
2.	Angiostrongyliasis 01/01/1997 - "Our previous in vivo studies on angiostrongyliasis showed that PF1022A had stronger killing effects against female adults than against males. "
3.	Helminthiasis (Helminthiases) 09/01/2013 - "The cyclooctadepsipeptide PF1022A and the aminophenylamidines amidantel, deacylated amidantel (dAMD) and tribendimidine were tested as examples for drug classes potentially interesting for development as anthelmintics against human helminthiases. "

Related Drugs and Biologics

1.	Pyrantel
2.	flubendazole
3.	Anthelmintics
4.	tribendimidine
5.	amidantel