|1.||Serrero, Ginette: 11 articles (01/2011 - 01/2003)|
|2.||Padovani, Alessandro: 10 articles (03/2015 - 10/2012)|
|3.||Borroni, Barbara: 10 articles (03/2015 - 10/2012)|
|4.||Archetti, Silvana: 10 articles (03/2015 - 10/2012)|
|5.||Cheung, Siu Tim: 10 articles (01/2015 - 11/2004)|
|6.||Fan, Sheung Tat: 10 articles (01/2015 - 11/2004)|
|7.||Premi, Enrico: 9 articles (05/2014 - 10/2012)|
|8.||Gasparotti, Roberto: 7 articles (02/2014 - 10/2012)|
|9.||Yip, Chi Wai: 6 articles (01/2015 - 01/2011)|
|10.||Cheung, Phyllis F Y: 6 articles (01/2015 - 01/2011)|
|1.||Frontotemporal Lobar Degeneration (Semantic Dementia)
07/01/2013 - "The neuroimaging signature of frontotemporal lobar degeneration associated with Granulin mutations: an effective connectivity study."
05/01/2013 - "Studies in asymptomatic granulin gene (GRN) mutation carriers are essential to improve our understanding of the pattern and timing of early morphologic brain changes in frontotemporal lobar degeneration. "
05/01/2014 - "Understanding phenotype variability in frontotemporal lobar degeneration due to granulin mutation."
07/01/2013 - "Mutations within Granulin (GRN) gene are causative of autosomal dominant frontotemporal lobar degeneration (FTLD). "
01/01/2013 - "Several causative gene mutations have been identified in frontotemporal lobar degeneration (FTLD), including mutations within Granulin (GRN) genes. "
01/01/2007 - "Functional studies on Hep-2 cell lines demonstrated that the attenuation of PC cell-derived growth factor expression levels led to diminished cell proliferation rates (P<0.001), anchorage-independent growth in vitro (P<0.001), tumor forming in vivo (P<0.01) and resistance to apoptosis (P<0.001). "
01/01/2015 - "Granulin-epithelin precursor (GEP), a secretory growth factor, demonstrated overexpression in various human cancers, however, mechanism remain elusive. "
12/01/2014 - "Granulin-epithelin precursor (GEP) overexpression has been shown in many cancers with functional role on growth, and recently on regulating chemoresistance and cancer stem cell (CSC) properties. "
11/01/2014 - "Granulin-epithelin precursor (GEP) is a pluripotent secretory growth factor which promotes cancer progression in a number of human cancers. "
01/01/2012 - "Granulin-epithelin precursor (GEP) has previously been reported to control cancer growth, invasion, chemo-resistance, and served as novel therapeutic target for cancer treatment. "
|3.||Liver Neoplasms (Liver Cancer)
01/01/2011 - "Gene expression profiling studies have shown that hepatic cancer cells express granulin-epithelin precursor (GEP); we investigated its role in hepatic cancer stem cell functions and chemoresistance. "
01/01/2015 - "Copy number gain of granulin-epithelin precursor (GEP) at chromosome 17q21 associates with overexpression in human liver cancer."
01/01/2011 - "Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells."
11/01/2014 - "Granulin-epithelin precursor interacts with heparan sulfate on liver cancer cells."
01/01/2011 - "Granulin-epithelin precursor and ATP-dependent binding cassette (ABC)B5 regulate liver cancer cell chemoresistance."
|4.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/01/2013 - "To investigate the effect of PC cell-derived growth factor (PCDGF) RNA interference on esophageal squamous carcinoma cells Eca-109 in vitro. "
09/01/2013 - "[Effect of PC cell-derived growth factor RNA interference on biological behavior of esophageal squamous carcinoma cells]."
01/01/2007 - "Our findings also indicate that PC cell-derived growth factor is a logical and potential target for early diagnosis, specific therapy and prognosis of laryngeal squamous cell carcinoma."
01/01/2007 - "PC cell-derived growth factor is a pivotal autocrine growth factor in the tumorigenesis of laryngeal squamous cell carcinoma. "
01/01/2007 - "No comprehensive literature concerning PC cell-derived growth factor expression status and its biological function in squamous cell carcinoma, especially in the larynx, is, however, available. "
|5.||Alzheimer Disease (Alzheimer's Disease)
07/05/2009 - "An association study between granulin gene polymorphisms and Alzheimer's disease in Finnish population."
01/01/2013 - "Genetic variants in the granulin (GRN) gene have been shown to increase the risk of Alzheimer's disease (AD). "
01/01/2013 - "GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients."
10/04/2011 - "Wnt effectors were tightly clustered with presenilin1 (PSEN1) and granulin (GRN), which cause dominantly inherited forms of Alzheimer's disease and frontotemporal dementia (FTD), respectively. "
10/01/2015 - "We investigated the contribution of rare variants in seven genes of known relevance to dementias (β-amyloid precursor protein (APP), PSEN1/2, MAPT (microtubule-associated protein tau), fused in sarcoma (FUS), granulin (GRN) and TAR DNA-binding protein 43 (TDP-43)) to PD and PD plus dementia (PD+D) in a discovery sample of 376 individuals with PD and followed by the genotyping of 25 out of the 27 identified variants with a minor allele frequency <5% in 975 individuals with PD, 93 cases with Lewy body disease on neuropathological examination, 613 individuals with Alzheimer's disease (AD), 182 cases with frontotemporal dementia and 1014 general population controls. "
|1.||tau Proteins (tau Protein)
|2.||Small Interfering RNA (siRNA)
|4.||granulin precursor protein
|7.||Complementary DNA (cDNA)
|8.||Staphylococcal Protein A (A, Protein)
|9.||Messenger RNA (mRNA)
|10.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)