olopatadine (Patanol)

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99 relevant articles (39 outcomes, 28 trials/studies) found for this Drug

Description: structure given in first source; analog of KW-4994; a prospective orally active antiallergic agent

Also Known As:

Patanol; 11-(3-(dimethylamino)propylidene)-6,11-dihydrodibenz(b,e)oxepin-2-acetic acid; Alcon Brand of Olopatadine Hydrochloride; KW 4679; KW-4679; KW-4943A; olopatadine hydrochloride

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 23

3-Ring Heterocyclic Compounds

Dibenzoxepins

olopatadine: 99

Experts

1.	Abelson, Mark B: 8 articles (12/2007 - 03/2003)
2.	Wall, G Michael: 5 articles (11/2007 - 11/2005)
3.	Robertson, Stella M: 4 articles (11/2007 - 08/2004)
4.	Tamura, Tadafumi: 3 articles (06/2008 - 12/2005)
5.	Roland, Peter S: 3 articles (11/2007 - 11/2005)
6.	Vogelson, Cullen T: 3 articles (11/2007 - 08/2004)
7.	Gross, Robert D: 3 articles (11/2007 - 08/2004)
8.	Drake, Margaret: 3 articles (11/2007 - 11/2005)
9.	Gomes, Paul J: 3 articles (07/2007 - 08/2004)
10.	Brubaker, Michael J: 3 articles (05/2006 - 11/2005)

Related Diseases

1.	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 09/01/1998 - "CONCLUSIONS: The results indicate that olopatadine ophthalmic solution is safe and effective in the treatment of allergic conjunctivitis, with the 0.1% concentration of olopatadine being optimal" 04/01/2003 - "CONCLUSIONS: As evidenced by significantly greater comfort and longer duration of lens wear, olopatadine provides superior comfort to contact lens wearers suffering from the signs and symptoms of seasonal allergic conjunctivitis, as induced by the CAC model." 10/01/2005 - "CONCLUSION: Olopatadine hydrochloride 0.1% is an effective agent for relieving the signs and symptoms of vernal keratoconjunctivitis" 09/10/2006 - "CONCLUSIONS: The anti-allergic eye drop olopatadine is a safe and effective treatment for seasonal allergic conjunctivitis even in childhood" 08/01/2004 - "Clinical efficacy of olopatadine hydrochloride ophthalmic solution 0.2% compared with placebo in patients with allergic conjunctivitis or rhinoconjunctivitis: a randomized, double-masked environmental study." Get all the results and reference details, order at left...
2.	Pruritus (Itching) 04/01/2008 - "RESULTS/CONCLUSION: Olopatadine 0.2% was found to be a safe and effective medication for the reduction of itching with a duration of action of up to 24 h" 12/01/2007 - "Efficacy of once-daily olopatadine 0.2% ophthalmic solution compared to twice-daily olopatadine 0.1% ophthalmic solution for the treatment of ocular itching induced by conjunctival allergen challenge." 12/01/2007 - "This double-masked conjunctival allergen challenge (CAC) study found no significant difference in the mean itching scores between two drops of olopatadine 0.1% and one drop of olopatadine 0.2%" 08/01/2003 - "However, the itching score was significantly lower in the olopatadine group from the second day through to the end of the study (p < 0.05)" 07/01/2007 - "Olopatadine 0.2% was significantly (p < 0.001) more effective than placebo in the treatment of ocular itching at all time points at both the onset of action and the 16-hour allergen challenges" Get all the results and reference details, order at left...
3.	Rhinitis 12/01/1995 - "These results indicate that KW-4679 may be useful for the treatment of allergic rhinitis." 12/01/2005 - "CONCLUSIONS: Olopatadine nasal spray (0.4% and 0.6%) provided statistically significant improvements in allergic rhinitis symptoms compared with placebo regarding TNSSs (reflective and instantaneous) and in quality-of-life variables in patients with SAR" 10/01/2005 - "Effects of adjuvant therapy with 0.1% olopatadine hydrochloride ophthalmic solution on quality of life in patients with allergic rhinitis using systemic or nasal therapy." 07/01/2001 - "Oral administration of olopatadine inhibited passive cutaneous anaphylaxis in rats, experimental allergic rhinitis and bronchial asthmatic responses in actively sensitized guinea pigs" 12/01/1995 - "The effect of KW-4679, an antiallergic drug, on experimental allergic rhinitis in guinea pigs: effects on nasal blockage." Get all the results and reference details, order at left...
4.	Urticaria (Hives) 04/01/2002 - "Olopatadine was shown to be useful for the treatment of allergic rhinitis and chronic urticaria in double-blind clinical trials" 07/01/2001 - "Olopatadine was shown to be useful for the treatment of allergic rhinitis and chronic urticaria in double-blind clinical trials" 11/01/2002 - "Olopatadine hydrochloride is one of the second-generation nonsedating antihistamines that are used for treating allergic disorders such as urticaria, rhinitis, and atopic dermatitis" 06/01/2001 - "Olopatadine hydrochloride (olopatadine), a novel antiallergic agent, is effective in the treatment of allergic rhinitis, chronic urticaria, eczema and dermatitis" 04/01/2002 - "Olopatadine was approved in Japan for the treatment of allergic rhinitis, chronic urticaria, eczema dermatitis, prurigo, pruritis cutaneous, psoriasis vulgaris and erythema exsudativum multiforme in December, 2000" Get all the results and reference details, order at left...
5.	Asthma (Bronchial Asthma) 11/01/1995 - "These observations indicate that KW-4679 attenuates the PAF-induced pulmonary reactions in guinea pigs and that these actions may be beneficial for the treatment of allergic bronchial asthma." 05/01/1996 - "These results indicate that KW-4679 could be useful in the treatment of allergic diseases such as bronchial asthma." 03/01/1996 - "These results indicate that KW-4679 could be useful in the treatment of bronchial asthma." 10/01/1995 - "These results indicate that KW-4679 might be useful in the treatment of allergic diseases such as asthma." 04/01/2002 - "Oral administration of olopatadine at doses of 0.03 mg/kg or higher inhibited the symptoms of experimental allergic skin responses, rhinoconjunctivitis and bronchial asthma in sensitized guinea pigs and rats" Get all the results and reference details, order at left...
36 Diseases and 99 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	olopatadine (Patanol)
2.	Ketotifen (Ketotifene)
3.	epinastine
4.	Histamine (Histamine Dihydrochloride)
5.	Antigens
6.	Ophthalmic Solutions (Eye Drops)
7.	Cromolyn Sodium (Cromoglicic Acid)
8.	Ketorolac
9.	levocabastine (Bilina)
10.	Histamine H1 Antagonists (Antihistamines)
62 Drugs and Important Bio-Agents and 64 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Contact Lenses
2.	Aftercare (After-Treatment)
2 Therapies and Procedures and 2 more articles analyzed in the Research Interface, order at left...

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